SGPP1 sphingosine-1-phosphate phosphatase 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: SGPP1provided by VGNC
Official Full Name: sphingosine-1-phosphate phosphatase 1provided by VGNC
Primary source: VGNC:VGNC:34548
See related: Ensembl:ENSBTAG00000004430
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	10	NC_037337.1 (75936963..75968043, complement)

Chromosome 10 - NC_037337.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables sphingosine-1-phosphate phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in phospholipid dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sphingosine metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: sphingosine-1-phosphate phosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077931.1 → NP_001071399.1 sphingosine-1-phosphate phosphatase 1

See identical proteins and their annotated locations for NP_001071399.1

Status: PROVISIONAL

Source sequence(s)

BC126582

UniProtKB/TrEMBL

A0JNA1

Related

ENSBTAP00000005808.3, ENSBTAT00000005808.4

Conserved Domains (2) summary

COG0671
Location:130 → 288

PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]

cd03388
Location:130 → 279

PAP2_SPPase1; PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an intracellular enzyme located in the endoplasmic reticulum, which regulates the level of sphingosine-1-phosphate (S1P), a bioactive lipid. S1P acts as a second ...