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PTRH2 peptidyl-tRNA hydrolase 2 [ Bos taurus (domestic cattle) ]

Gene ID: 516595, updated on 4-Oct-2024

Summary

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Official Symbol
PTRH2provided by VGNC
Official Full Name
peptidyl-tRNA hydrolase 2provided by VGNC
Primary source
VGNC:VGNC:33562
See related
BGD:BT22027; Ensembl:ENSBTAG00000055796
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
BIT1
Orthologs
human mouse all
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Genomic context

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See PTRH2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (10665273..10674104, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132343002 Neighboring gene DEAH-box helicase 40 Neighboring gene clathrin heavy chain Neighboring gene vacuole membrane protein 1 Neighboring gene microRNA mir-21

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
  2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC128626

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aminoacyl-tRNA hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of anoikis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of anoikis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
peptidyl-tRNA hydrolase 2, mitochondrial
Names
Bcl-2 inhibitor of transcription
PTH 2
NP_001029691.1
XP_005219951.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034519.1 → NP_001029691.1  peptidyl-tRNA hydrolase 2, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001029691.1

    Status: PROVISIONAL

    Source sequence(s)
    BT021191
    UniProtKB/TrEMBL
    A0AAA9TY37
    Related
    ENSBTAP00000083810.1, ENSBTAT00000135417.1
    Conserved Domains (1) summary
    cd02430
    Location:65 → 179
    PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    10665273..10674104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005219894.5 → XP_005219951.1  peptidyl-tRNA hydrolase 2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_005219951.1

    UniProtKB/Swiss-Prot
    Q05KI4, Q3ZBL5, Q5BIN3
    UniProtKB/TrEMBL
    A0AAA9TY37
    Related
    ENSBTAP00000085563.1, ENSBTAT00000096422.1
    Conserved Domains (1) summary
    cd02430
    Location:65 → 179
    PTH2; Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3ZBL5.1 GenPept UniProtKB/Swiss-Prot:Q3ZBL5

Gene LinkOut

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