LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: LAMTOR5provided by VGNC
Official Full Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5provided by VGNC
Primary source: VGNC:VGNC:55244
See related: BGD:BT22362; Ensembl:ENSBTAG00000014970
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: HBXIP
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (33026800..33031126)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Overall, the available data depict a self-inhibitory feedback loop in which HBV, through HBx, increases the expression of miR-125a, that in turn interferes with expression of HBV surface antigen, thus repressing viral replication.
Title: Functional interplay between hepatitis B virus X protein and human miR-125a in HBV infection.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to amino acid stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of TORC1 signaling	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of Ragulator complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in lysosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ragulator complex protein LAMTOR5

Names: HBV X-interacting protein homolog; HBX-interacting protein homolog; hepatitis B virus X-interacting protein homolog; hepatitis B virus x interacting protein; late endosomal/lysosomal adaptor and MAPK and MTOR activator 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.