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SESN3 sestrin 3 [ Bos taurus (domestic cattle) ]

Gene ID: 515914, updated on 4-Oct-2024

Summary

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Official Symbol
SESN3provided by VGNC
Official Full Name
sestrin 3provided by VGNC
Primary source
VGNC:VGNC:34490
See related
BGD:BT13420; Ensembl:ENSBTAG00000004034
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See SESN3 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (15191004..15271904)

Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342303 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC101906086 Neighboring gene endonuclease domain containing 1 Neighboring gene uncharacterized LOC132342305

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-leucine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on peroxide as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to L-leucine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to leucine starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of response to reactive oxygen species IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sestrin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    15191004..15271904
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059875066.1 → XP_059731049.1  sestrin-3 isoform X3

    Related
    ENSBTAP00000078774.1, ENSBTAT00000129388.1

  2. XM_024975718.2 → XP_024831486.1  sestrin-3 isoform X1

    UniProtKB/TrEMBL
    A0AAA9SC09
    Related
    ENSBTAP00000083639.1, ENSBTAT00000088066.1
    Conserved Domains (1) summary
    pfam04636
    Location:73 → 524
    PA26; PA26 p53-induced protein (sestrin)

  3. XM_024975719.2 → XP_024831487.1  sestrin-3 isoform X2

    UniProtKB/TrEMBL
    F1MFJ7
    Related
    ENSBTAP00000005267.6, ENSBTAT00000005267.7
    Conserved Domains (1) summary
    pfam04636
    Location:39 → 490
    PA26; PA26 p53-induced protein (sestrin)
Nucleotide Protein Strain
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Gene LinkOut

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Molecular Biology Databases
Research Materials