RECQL4 RecQ like helicase 4 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: RECQL4provided by VGNC
Official Full Name: RecQ like helicase 4provided by VGNC
Primary source: VGNC:VGNC:33849
See related: BGD:BT27211; Ensembl:ENSBTAG00000010276
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: RTS; RecQ4
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	14	NC_037341.1 (428460..434942)

Chromosome 14 - NC_037341.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 3'-5' DNA helicase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables four-way junction helicase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in DNA unwinding involved in DNA replication	IEA Inferred from Electronic Annotation more info	PubMed
involved_in double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in telomere maintenance	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in chromosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ATP-dependent DNA helicase Q4

Names: RecQ protein-like 4

NP_001091506.1

EC 3.6.4.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001098037.2 → NP_001091506.1 ATP-dependent DNA helicase Q4

See identical proteins and their annotated locations for NP_001091506.1

Status: PROVISIONAL

Source sequence(s)

BC140466

UniProtKB/TrEMBL

A0AAA9S7V9, A5D786, E1BD48

Related

ENSBTAP00000075303.1, ENSBTAT00000133193.1

Conserved Domains (3) summary

smart00487
Location:487 → 670

DEXDc; DEAD-like helicases superfamily

cd00079
Location:689 → 831

HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...

pfam00270
Location:496 → 661

DEAD; DEAD/DEAH box helicase