DOK1 docking protein 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: DOK1provided by VGNC
Official Full Name: docking protein 1provided by VGNC
Primary source: VGNC:VGNC:28165
See related: BGD:BT11545; Ensembl:ENSBTAG00000018579
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	11	NC_037338.1 (10085661..10088549, complement)

Chromosome 11 - NC_037338.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of MAPK cascade	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: docking protein 1

Names: downstream of tyrosine kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024543.2 → NP_001019714.2 docking protein 1

See identical proteins and their annotated locations for NP_001019714.2

Status: PROVISIONAL

Source sequence(s)

BT020685

UniProtKB/Swiss-Prot

Q5EA84

UniProtKB/TrEMBL

F1MRT5

Related

ENSBTAP00000024727.4, ENSBTAT00000024727.5

Conserved Domains (3) summary

cd01203
Location:151 → 253

PTB_DOK1_DOK2_DOK3; Downstream of tyrosine kinase 1, 2, and 3 proteins phosphotyrosine-binding domain (PTBi)

cd14676
Location:6 → 119

PH_DOK1,2,3; Pleckstrin homology (PH) domain of Downstream of tyrosine kinase 1, 2, and 3

pfam00169
Location:5 → 116

PH; PH domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

Range

10085661..10088549 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024998581.2 → XP_024854349.1 docking protein 1 isoform X1

Conserved Domains (1) summary

cl17171
Location:1 → 39

PH-like; Pleckstrin homology-like domain