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PHF21A PHD finger protein 21A [ Homo sapiens (human) ]

Gene ID: 51317, updated on 2-Nov-2024

Summary

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Official Symbol
PHF21Aprovided by HGNC
Official Full Name
PHD finger protein 21Aprovided by HGNC
Primary source
HGNC:HGNC:24156
See related
Ensembl:ENSG00000135365 MIM:608325; AllianceGenome:HGNC:24156
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BHC80; NEDMS; BM-006; IDDBCS
Summary
The PHF21A gene encodes BHC80, a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002 [PubMed 12032298]).[supplied by OMIM, Nov 2010]
Expression
Ubiquitous expression in testis (RPKM 7.2), ovary (RPKM 5.9) and 25 other tissues See more
Orthologs
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Genomic context

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See PHF21A in Genome Data Viewer
Location:
11p11.2
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (45929319..46121454, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (46085233..46277451, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (45950870..46143005, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:45938484-45939236 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3292 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4673 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4674 Neighboring gene peroxisomal biogenesis factor 16 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:45956286-45957284 Neighboring gene LARGE xylosyl- and glucuronyltransferase 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:45975728-45975893 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:45986871-45987068 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:46003193-46004090 Neighboring gene Sharpr-MPRA regulatory region 8215 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:46015337-46015518 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:46015959-46016504 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:46022272-46022894 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:46033641-46034224 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:46141064-46141221 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3293 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3294 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3295 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3296 Neighboring gene uncharacterized LOC105376661 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:46164759-46165418 Neighboring gene FBLIM1 pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Transcriptome Analysis Revealed Impaired cAMP Responsiveness in PHF21A-Deficient Human Cells. Porter RS, et al. Neuroscience, 2018 Feb 1. PMID 28571721, Free PMC Article
  2. Disruption of PHF21A causes syndromic intellectual disability with craniofacial anomalies, epilepsy, hypotonia, and neurobehavioral problems including autism. Kim HG, et al. Mol Autism, 2019. PMID 31649809, Free PMC Article
  3. A novel de novo variant in the PHF21A causes craniofacial abnormalities, intellectual disability and skeletal manifestations. Mustafa S, et al. Clin Genet, 2023 Jul. PMID 36843358
  4. Potocki-Shaffer syndrome in a child without intellectual disability-The role of PHF21A in cognitive function. McCool C, et al. Am J Med Genet A, 2017 Mar. PMID 28127865
  5. PHF21A Related Disorder: Description of a New Case. Butera A, et al. Int J Mol Sci, 2022 Dec 17. PMID 36555772, Free PMC Article

See all (72) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A novel de novo variant in the PHF21A causes craniofacial abnormalities, intellectual disability and skeletal manifestations.
    Title: A novel de novo variant in the PHF21A causes craniofacial abnormalities, intellectual disability and skeletal manifestations.
  2. PHF21A expression as a biomarker of hepatocellular carcinoma progression and prognosis.
    Title: PHF21A expression as a biomarker of hepatocellular carcinoma progression and prognosis.
  3. RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression.
    Title: RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression.
  4. PHF21A is involved in autism spectrum disorder and intellectual disability, and its haploinsufficiency causes a diverse neurological phenotype.
    Title: Disruption of PHF21A causes syndromic intellectual disability with craniofacial anomalies, epilepsy, hypotonia, and neurobehavioral problems including autism.
  5. PHF21A truncating mutations were identified in three patients with intellectual disability and craniofacial anomalies.
    Title: De novo truncating variants in PHF21A cause intellectual disability and craniofacial anomalies.
  6. Study analyzed by RNA-Sequencing (RNA-Seq) two patient-derived cell lines with heterozygous loss of PHF21A compared to unaffected individuals and identified 1,885 genes that were commonly misregulated. The patient cells displayed down-regulation of key pathways relevant to learning and memory, including Cyclic Adenosine Monophosphate (cAMP)-signaling pathway genes.
    Title: Transcriptome Analysis Revealed Impaired cAMP Responsiveness in PHF21A-Deficient Human Cells.
  7. this case lends further support that haploinsufficiency of PHF21A contributes to the intellectual disability and craniofacial abnormalities in PSS and that there are other genes in the region which likely contribute to the behavioral phenotype in this syndrome.
    Title: Potocki-Shaffer syndrome in a child without intellectual disability-The role of PHF21A in cognitive function.
  8. we have uncovered evidence that the ID and CFA phenotypes are both caused by haploinsufficiency of a single gene, PHF21A, at 11p11.2.
    Title: Translocations disrupting PHF21A in the Potocki-Shaffer-syndrome region are associated with intellectual disability and craniofacial anomalies.
  9. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
  10. the recovery of neurosecretion depends on the reciprocal level of BHC80 and REST, with BHC80 working as a negative modulator of REST repression
    Title: The rest repression of the neurosecretory phenotype is negatively modulated by BHC80, a protein of the BRAF/HDAC complex.
Submit: New GeneRIF Correction See all GeneRIFs (11)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures
MedGen: C5231476 OMIM: 618725 GeneReviews: Not available
not available

Copy number response

Description
Copy number response
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated 2023-09-21)

ClinGen Genome Curation PagePubMed
Triplosensitivity

No evidence available (Last evaluated 2023-09-21)

ClinGen Genome Curation Page

EBI GWAS Catalog

Description
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
EBI GWAS Catalog
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
EBI GWAS Catalog
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • KIAA1696

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA repair complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of histone deacetylase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of histone deacetylase complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleoplasm TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
PHD finger protein 21A
Names
BHC80a
BRAF35-HDAC complex protein BHC80
BRAF35/HDAC2 complex (80 kDa)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101802.3 → NP_001095272.1  PHD finger protein 21A isoform a

    See identical proteins and their annotated locations for NP_001095272.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform a.
    Source sequence(s)
    AC024475, AC068385
    Consensus CDS
    CCDS44578.1
    UniProtKB/Swiss-Prot
    D3DQP5, Q6AWA2, Q96BD5, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9
    UniProtKB/TrEMBL
    H0YEK2
    Related
    ENSP00000398824.2, ENST00000418153.6
    Conserved Domains (2) summary
    COG5034
    Location:374 → 536
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:490 → 532
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  2. NM_001352025.3 → NP_001338954.1  PHD finger protein 21A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (c). Variants 3, 4, and 5 all encode isoform c.
    Source sequence(s)
    AC024475, AC068385
    Consensus CDS
    CCDS91465.1
    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (2) summary
    COG5034
    Location:375 → 537
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:491 → 533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  3. NM_001352026.3 → NP_001338955.1  PHD finger protein 21A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variants 3 and 5, encodes isoform c.
    Source sequence(s)
    AC024475, AC068385
    Consensus CDS
    CCDS91465.1
    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (2) summary
    COG5034
    Location:375 → 537
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:491 → 533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  4. NM_001352027.3 → NP_001338956.1  PHD finger protein 21A isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 3 and 4, encodes isoform c.
    Source sequence(s)
    AC024475, AC068385
    Consensus CDS
    CCDS91465.1
    UniProtKB/TrEMBL
    H0YEK2
    Related
    ENSP00000502222.1, ENST00000676320.1
    Conserved Domains (2) summary
    COG5034
    Location:375 → 537
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:491 → 533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  5. NM_001352028.1 → NP_001338957.1  PHD finger protein 21A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variants 2 and 7, encodes isoform b.
    Source sequence(s)
    AC024475, AC068385
    Consensus CDS
    CCDS31474.1
    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (1) summary
    cd15523
    Location:444 → 486
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  6. NM_001352029.1 → NP_001338958.1  PHD finger protein 21A isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 2 and 6, encodes isoform b.
    Source sequence(s)
    AC024475, AC068385
    Consensus CDS
    CCDS31474.1
    UniProtKB/TrEMBL
    H0YEK2
    Related
    ENSP00000508589.1, ENST00000690620.1
    Conserved Domains (1) summary
    cd15523
    Location:444 → 486
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  7. NM_001352030.3 → NP_001338959.1  PHD finger protein 21A isoform 8

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 9 and 10, encodes isoform d.
    Source sequence(s)
    AC024475, AC068385
    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (1) summary
    cd15523
    Location:443 → 485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  8. NM_001352031.3 → NP_001338960.1  PHD finger protein 21A isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9), as well as variants 8 and 10, encodes isoform d.
    Source sequence(s)
    AC024475, AC068385
    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (1) summary
    cd15523
    Location:443 → 485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  9. NM_001352032.3 → NP_001338961.1  PHD finger protein 21A isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variants 8 and 9, encodes isoform d.
    Source sequence(s)
    AC024475, AC068385
    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (1) summary
    cd15523
    Location:443 → 485
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  10. NM_016621.5 → NP_057705.3  PHD finger protein 21A isoform b

    See identical proteins and their annotated locations for NP_057705.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the mid-coding region, and includes an alternate in-frame exon in the 3' coding region, but lacks a different alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting protein (isoform b) is shorter than isoform a. Variants 2, 6, and 7 all encode the same isoform (b).
    Source sequence(s)
    AB051483, AC024475, AC068385
    Consensus CDS
    CCDS31474.1
    UniProtKB/TrEMBL
    H0YEK2
    Related
    ENSP00000323152.6, ENST00000323180.10
    Conserved Domains (1) summary
    cd15523
    Location:444 → 486
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

RNA

  1. NR_147890.3 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC024475, AC068385

  2. NR_165446.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC024475, AC068385

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    45929319..46121454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047427091.1 → XP_047283047.1  PHD finger protein 21A isoform X8

  2. XM_047427108.1 → XP_047283064.1  PHD finger protein 21A isoform X19

  3. XM_047427085.1 → XP_047283041.1  PHD finger protein 21A isoform X6

  4. XM_047427109.1 → XP_047283065.1  PHD finger protein 21A isoform X18

  5. XM_047427105.1 → XP_047283061.1  PHD finger protein 21A isoform X17

  6. XM_047427094.1 → XP_047283050.1  PHD finger protein 21A isoform X9

  7. XM_047427081.1 → XP_047283037.1  PHD finger protein 21A isoform X2

  8. XM_047427082.1 → XP_047283038.1  PHD finger protein 21A isoform X3

  9. XM_047427098.1 → XP_047283054.1  PHD finger protein 21A isoform X12

  10. XM_011520157.3 → XP_011518459.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518459.1

    Conserved Domains (2) summary
    cd15523
    Location:498 → 540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382 → 544
    ING; Inhibitor of growth proteins N-terminal histone-binding

  11. XM_017017907.2 → XP_016873396.1  PHD finger protein 21A isoform X22

    Conserved Domains (3) summary
    COG5034
    Location:291 → 453
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:407 → 449
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    pfam01017
    Location:3 → 62
    STAT_alpha; STAT protein, all-alpha domain

  12. XM_047427090.1 → XP_047283046.1  PHD finger protein 21A isoform X8

  13. XM_017017892.2 → XP_016873381.1  PHD finger protein 21A isoform X6

    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (2) summary
    COG5034
    Location:374 → 536
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:490 → 532
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  14. XM_047427107.1 → XP_047283063.1  PHD finger protein 21A isoform X18

  15. XM_017017891.2 → XP_016873380.1  PHD finger protein 21A isoform X7

    UniProtKB/Swiss-Prot
    D3DQP5, Q6AWA2, Q96BD5, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9
    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (2) summary
    COG5034
    Location:374 → 536
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:490 → 532
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  16. XM_047427104.1 → XP_047283060.1  PHD finger protein 21A isoform X17

  17. XM_047427092.1 → XP_047283048.1  PHD finger protein 21A isoform X9

  18. XM_011520179.4 → XP_011518481.1  PHD finger protein 21A isoform X14

    See identical proteins and their annotated locations for XP_011518481.1

    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (1) summary
    cd15523
    Location:444 → 486
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  19. XM_017017889.2 → XP_016873378.1  PHD finger protein 21A isoform X2

    Conserved Domains (2) summary
    cd15523
    Location:497 → 539
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:381 → 543
    ING; Inhibitor of growth proteins N-terminal histone-binding

  20. XM_011520158.3 → XP_011518460.1  PHD finger protein 21A isoform X1

    See identical proteins and their annotated locations for XP_011518460.1

    Conserved Domains (2) summary
    cd15523
    Location:498 → 540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382 → 544
    ING; Inhibitor of growth proteins N-terminal histone-binding

  21. XM_047427087.1 → XP_047283043.1  PHD finger protein 21A isoform X6

  22. XM_047427102.1 → XP_047283058.1  PHD finger protein 21A isoform X15

    Related
    ENSP00000431964.2, ENST00000525676.6

  23. XM_047427110.1 → XP_047283066.1  PHD finger protein 21A isoform X18

  24. XM_047427089.1 → XP_047283045.1  PHD finger protein 21A isoform X7

    UniProtKB/Swiss-Prot
    D3DQP5, Q6AWA2, Q96BD5, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9

  25. XM_005252965.5 → XP_005253022.1  PHD finger protein 21A isoform X5

    See identical proteins and their annotated locations for XP_005253022.1

    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (2) summary
    COG5034
    Location:375 → 537
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:491 → 533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  26. XM_047427101.1 → XP_047283057.1  PHD finger protein 21A isoform X14

  27. XM_017017887.3 → XP_016873376.1  PHD finger protein 21A isoform X1

    Conserved Domains (2) summary
    cd15523
    Location:498 → 540
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)
    cl26267
    Location:382 → 544
    ING; Inhibitor of growth proteins N-terminal histone-binding

  28. XM_011520175.3 → XP_011518477.1  PHD finger protein 21A isoform X6

    See identical proteins and their annotated locations for XP_011518477.1

    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (2) summary
    COG5034
    Location:374 → 536
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:490 → 532
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  29. XM_011520174.3 → XP_011518476.1  PHD finger protein 21A isoform X5

    See identical proteins and their annotated locations for XP_011518476.1

    UniProtKB/TrEMBL
    H0YEK2
    Conserved Domains (2) summary
    COG5034
    Location:375 → 537
    TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
    cd15523
    Location:491 → 533
    PHD_PHF21A; PHD finger found in PHD finger protein 21A (PHF21A)

  30. XM_047427093.1 → XP_047283049.1  PHD finger protein 21A isoform X9

  31. XM_047427100.1 → XP_047283056.1  PHD finger protein 21A isoform X14

  32. XM_047427088.1 → XP_047283044.1  PHD finger protein 21A isoform X6

  33. XM_047427084.1 → XP_047283040.1  PHD finger protein 21A isoform X5

  34. XM_047427079.1 → XP_047283035.1  PHD finger protein 21A isoform X1

  35. XM_047427086.1 → XP_047283042.1  PHD finger protein 21A isoform X7

    UniProtKB/Swiss-Prot
    D3DQP5, Q6AWA2, Q96BD5, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9

  36. XM_047427080.1 → XP_047283036.1  PHD finger protein 21A isoform X1

  37. XM_047427103.1 → XP_047283059.1  PHD finger protein 21A isoform X16

  38. XM_047427083.1 → XP_047283039.1  PHD finger protein 21A isoform X4

  39. XM_047427097.1 → XP_047283053.1  PHD finger protein 21A isoform X11

  40. XM_047427099.1 → XP_047283055.1  PHD finger protein 21A isoform X13

  41. XM_047427095.1 → XP_047283051.1  PHD finger protein 21A isoform X10

  42. XM_047427113.1 → XP_047283069.1  PHD finger protein 21A isoform X21

  43. XM_047427111.1 → XP_047283067.1  PHD finger protein 21A isoform X20

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    46085233..46277451 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054369083.1 → XP_054225058.1  PHD finger protein 21A isoform X8

  2. XM_054369099.1 → XP_054225074.1  PHD finger protein 21A isoform X19

  3. XM_054369076.1 → XP_054225051.1  PHD finger protein 21A isoform X6

  4. XM_054369100.1 → XP_054225075.1  PHD finger protein 21A isoform X18

  5. XM_054369097.1 → XP_054225072.1  PHD finger protein 21A isoform X17

  6. XM_054369086.1 → XP_054225061.1  PHD finger protein 21A isoform X9

  7. XM_054369068.1 → XP_054225043.1  PHD finger protein 21A isoform X2

  8. XM_054369069.1 → XP_054225044.1  PHD finger protein 21A isoform X3

  9. XM_054369089.1 → XP_054225064.1  PHD finger protein 21A isoform X12

  10. XM_054369062.1 → XP_054225037.1  PHD finger protein 21A isoform X1

  11. XM_054369104.1 → XP_054225079.1  PHD finger protein 21A isoform X22

  12. XM_054369082.1 → XP_054225057.1  PHD finger protein 21A isoform X8

  13. XM_054369074.1 → XP_054225049.1  PHD finger protein 21A isoform X6

  14. XM_054369098.1 → XP_054225073.1  PHD finger protein 21A isoform X18

  15. XM_054369075.1 → XP_054225050.1  PHD finger protein 21A isoform X7

    UniProtKB/Swiss-Prot
    D3DQP5, Q6AWA2, Q96BD5, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9

  16. XM_054369096.1 → XP_054225071.1  PHD finger protein 21A isoform X17

  17. XM_054369084.1 → XP_054225059.1  PHD finger protein 21A isoform X9

  18. XM_054369091.1 → XP_054225066.1  PHD finger protein 21A isoform X14

  19. XM_054369067.1 → XP_054225042.1  PHD finger protein 21A isoform X2

  20. XM_054369064.1 → XP_054225039.1  PHD finger protein 21A isoform X1

  21. XM_054369101.1 → XP_054225076.1  PHD finger protein 21A isoform X18

  22. XM_054369094.1 → XP_054225069.1  PHD finger protein 21A isoform X15

  23. XM_054369063.1 → XP_054225038.1  PHD finger protein 21A isoform X1

  24. XM_054369065.1 → XP_054225040.1  PHD finger protein 21A isoform X1

  25. XM_054369066.1 → XP_054225041.1  PHD finger protein 21A isoform X1

  26. XM_054369078.1 → XP_054225053.1  PHD finger protein 21A isoform X6

  27. XM_054369080.1 → XP_054225055.1  PHD finger protein 21A isoform X7

    UniProtKB/Swiss-Prot
    D3DQP5, Q6AWA2, Q96BD5, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9

  28. XM_054369093.1 → XP_054225068.1  PHD finger protein 21A isoform X14

  29. XM_054369081.1 → XP_054225056.1  PHD finger protein 21A isoform X6

  30. XM_054369085.1 → XP_054225060.1  PHD finger protein 21A isoform X9

  31. XM_054369092.1 → XP_054225067.1  PHD finger protein 21A isoform X14

  32. XM_054369079.1 → XP_054225054.1  PHD finger protein 21A isoform X6

  33. XM_054369077.1 → XP_054225052.1  PHD finger protein 21A isoform X7

    UniProtKB/Swiss-Prot
    D3DQP5, Q6AWA2, Q96BD5, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9

  34. XM_054369073.1 → XP_054225048.1  PHD finger protein 21A isoform X5

  35. XM_054369071.1 → XP_054225046.1  PHD finger protein 21A isoform X5

  36. XM_054369072.1 → XP_054225047.1  PHD finger protein 21A isoform X5

  37. XM_054369095.1 → XP_054225070.1  PHD finger protein 21A isoform X16

  38. XM_054369070.1 → XP_054225045.1  PHD finger protein 21A isoform X4

  39. XM_054369088.1 → XP_054225063.1  PHD finger protein 21A isoform X11

  40. XM_054369090.1 → XP_054225065.1  PHD finger protein 21A isoform X13

  41. XM_054369087.1 → XP_054225062.1  PHD finger protein 21A isoform X10

  42. XM_054369103.1 → XP_054225078.1  PHD finger protein 21A isoform X21

  43. XM_054369102.1 → XP_054225077.1  PHD finger protein 21A isoform X20

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96BD5.1 GenPept UniProtKB/Swiss-Prot:Q96BD5

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