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MMP17 matrix metallopeptidase 17 [ Bos taurus (domestic cattle) ]

Gene ID: 513072, updated on 4-Oct-2024

Summary

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Official Symbol
MMP17provided by VGNC
Official Full Name
matrix metallopeptidase 17provided by VGNC
Primary source
VGNC:VGNC:31522
See related
BGD:BT11172; Ensembl:ENSBTAG00000002145
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See MMP17 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (45239938..45266416, complement)

Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene pseudouridine synthase 1 Neighboring gene unc-51 like autophagy activating kinase 1 Neighboring gene splicing factor SWAP Neighboring gene microRNA mir-2285af-2 Neighboring gene uncharacterized LOC132342605

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
matrix metalloproteinase-17
Names
matrix metallopeptidase 17 (membrane-inserted)
XP_002694502.1
XP_024833427.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    45239938..45266416 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024977659.2 → XP_024833427.1  matrix metalloproteinase-17 isoform X2

    Conserved Domains (3) summary
    cd00094
    Location:270 → 464
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:127 → 231
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:42 → 100
    PG_binding_1; Putative peptidoglycan binding domain

  2. XM_002694456.7 → XP_002694502.1  matrix metalloproteinase-17 isoform X1

    See identical proteins and their annotated locations for XP_002694502.1

    UniProtKB/TrEMBL
    E1BH36
    Related
    ENSBTAP00000029696.3, ENSBTAT00000029698.5
    Conserved Domains (4) summary
    cd00094
    Location:329 → 523
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:127 → 290
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam00413
    Location:127 → 290
    Peptidase_M10; Matrixin
    pfam01471
    Location:42 → 100
    PG_binding_1; Putative peptidoglycan binding domain
Nucleotide Protein Strain
Heading Accession and Version

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