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ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 [ Bos taurus (domestic cattle) ]

Gene ID: 512010, updated on 4-Oct-2024

Summary

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Official Symbol
ARAP2provided by VGNC
Official Full Name
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2provided by VGNC
Primary source
VGNC:VGNC:26055
See related
BGD:BT25016; Ensembl:ENSBTAG00000039922
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See ARAP2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (55443414..55640423, complement)

Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC781670 Neighboring gene uncharacterized LOC132345496 Neighboring gene uncharacterized LOC112447062 Neighboring gene death domain containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    55443414..55640423 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059887745.1 → XP_059743728.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LV13
    Related
    ENSBTAP00000061021.2, ENSBTAT00000077281.2

  2. XM_059887746.1 → XP_059743729.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    F1MTN6
    Related
    ENSBTAP00000044378.5, ENSBTAT00000047153.5

  3. XM_024993531.2 → XP_024849299.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M293
    Related
    ENSBTAP00000064127.2, ENSBTAT00000081161.2
    Conserved Domains (10) summary
    cd09490
    Location:6 → 68
    SAM_Arap1,2,3; SAM domain of Arap1,2,3 (angiotensin receptor-associated protein)
    cd04385
    Location:1133 → 1312
    RhoGAP_ARAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their ArfGAP activity ...
    pfam05311
    Location:311 → 462
    Baculo_PP31; Baculovirus 33KDa late protein (PP31)
    cd13253
    Location:485 → 595
    PH1_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 1
    cd13254
    Location:606 → 694
    PH2_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 2
    cd13256
    Location:911 → 1021
    PH3_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 3
    cd13259
    Location:1442 → 1562
    PH5_ARAP; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain, repeat 5
    pfam01412
    Location:705 → 820
    ArfGap; Putative GTPase activating protein for Arf
    cl17171
    Location:1034 → 1129
    PH-like; Pleckstrin homology-like domain
    cl25424
    Location:1349 → 1436
    TGS; The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information ...

  4. XM_059887747.1 → XP_059743730.1  arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X4

RNA

  1. XR_009494861.1 RNA Sequence

  2. XR_009494862.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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