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DGKZ diacylglycerol kinase zeta [ Bos taurus (domestic cattle) ]

Gene ID: 511887, updated on 10-Oct-2024

Summary

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Official Symbol
DGKZprovided by VGNC
Official Full Name
diacylglycerol kinase zetaprovided by VGNC
Primary source
VGNC:VGNC:54417
See related
Ensembl:ENSBTAG00000013636
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See DGKZ in Genome Data Viewer
Location:
chromosome: 15
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (76331079..76374697)

Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene LARGE xylosyl- and glucuronyltransferase 2 Neighboring gene PHD finger protein 21A Neighboring gene uncharacterized LOC132342366 Neighboring gene cAMP responsive element binding protein 3 like 1 Neighboring gene cholinergic receptor muscarinic 4 Neighboring gene autophagy and beclin 1 regulator 1 Neighboring gene midkine Neighboring gene transcription initiation factor TFIID subunit 9-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase zeta
Names
diacylglycerol kinase, zeta 104kDa
NP_001265581.1
XP_024830955.2
XP_024830957.1
XP_024830959.1
XP_024830960.2
XP_024830962.1
XP_024830963.1
XP_024830964.1
XP_024830965.1
XP_024830966.1
XP_059730646.1
XP_059730647.1
XP_059730648.1
XP_059730649.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001278652.1 → NP_001265581.1  diacylglycerol kinase zeta

    Status: VALIDATED

    Source sequence(s)
    BC151801, BI536253, DV820601, DV910887, EE348312, EH208627
    UniProtKB/TrEMBL
    A0A3Q1N653
    Conserved Domains (7) summary
    smart00045
    Location:446 → 603
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:297 → 418
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:293 → 616
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00204
    Location:794 → 910
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:794 → 888
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:794 → 820
    ANK; ANK repeat [structural motif]
    cl00040
    Location:172 → 231
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    76331079..76374697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024975194.2 → XP_024830962.1  diacylglycerol kinase zeta isoform X6

    UniProtKB/TrEMBL
    A0A3Q1N653
    Conserved Domains (5) summary
    smart00045
    Location:457 → 614
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:308 → 429
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00204
    Location:805 → 921
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:805 → 831
    ANK; ANK repeat [structural motif]
    cl00040
    Location:183 → 242
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

  2. XM_024975195.2 → XP_024830963.1  diacylglycerol kinase zeta isoform X7

    UniProtKB/TrEMBL
    A0A3Q1N653, A0AAA9T617
    Related
    ENSBTAP00000093304.1, ENSBTAT00000117952.1
    Conserved Domains (5) summary
    smart00045
    Location:456 → 613
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:307 → 428
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00204
    Location:804 → 920
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:804 → 830
    ANK; ANK repeat [structural motif]
    cl00040
    Location:182 → 241
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

  3. XM_024975196.2 → XP_024830964.1  diacylglycerol kinase zeta isoform X8

    UniProtKB/TrEMBL
    A0A3Q1N531, A0A3Q1N653
    Related
    ENSBTAP00000065108.2, ENSBTAT00000066491.2
    Conserved Domains (5) summary
    smart00045
    Location:452 → 609
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:303 → 424
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00204
    Location:800 → 916
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:800 → 826
    ANK; ANK repeat [structural motif]
    cl00040
    Location:178 → 237
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

  4. XM_024975197.2 → XP_024830965.1  diacylglycerol kinase zeta isoform X9

    UniProtKB/TrEMBL
    A0A3Q1N653
    Conserved Domains (5) summary
    smart00045
    Location:451 → 608
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:302 → 423
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00204
    Location:799 → 915
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:799 → 825
    ANK; ANK repeat [structural motif]
    cl00040
    Location:177 → 236
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

  5. XM_024975189.2 → XP_024830957.1  diacylglycerol kinase zeta isoform X3

    UniProtKB/TrEMBL
    A0AAA9SCA8
    Related
    ENSBTAP00000081507.1, ENSBTAT00000123014.1
    Conserved Domains (5) summary
    smart00045
    Location:702 → 859
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:553 → 674
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00204
    Location:1050 → 1166
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00130
    Location:428 → 487
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    sd00045
    Location:1050 → 1076
    ANK; ANK repeat [structural motif]

  6. XM_024975198.2 → XP_024830966.1  diacylglycerol kinase zeta isoform X10

    UniProtKB/TrEMBL
    A0A3Q1N653
    Related
    ENSBTAP00000065885.2, ENSBTAT00000075478.2
    Conserved Domains (5) summary
    smart00045
    Location:447 → 604
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:298 → 419
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00204
    Location:795 → 911
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:795 → 821
    ANK; ANK repeat [structural motif]
    cl00040
    Location:173 → 232
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

  7. XM_059874663.1 → XP_059730646.1  diacylglycerol kinase zeta isoform X1

  8. XM_024975187.2 → XP_024830955.2  diacylglycerol kinase zeta isoform X2

  9. XM_024975192.2 → XP_024830960.2  diacylglycerol kinase zeta isoform X5

  10. XM_059874664.1 → XP_059730647.1  diacylglycerol kinase zeta isoform X4

    UniProtKB/TrEMBL
    G5E5G8

  11. XM_059874665.1 → XP_059730648.1  diacylglycerol kinase zeta isoform X11

  12. XM_059874666.1 → XP_059730649.1  diacylglycerol kinase zeta isoform X11

  13. XM_024975191.2 → XP_024830959.1  diacylglycerol kinase zeta isoform X4

    UniProtKB/TrEMBL
    G5E5G8
    Related
    ENSBTAP00000018128.7, ENSBTAT00000018128.7
    Conserved Domains (5) summary
    smart00045
    Location:642 → 799
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:493 → 614
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00204
    Location:990 → 1106
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00130
    Location:368 → 427
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    sd00045
    Location:990 → 1016
    ANK; ANK repeat [structural motif]
Nucleotide Protein Strain
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