ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: ADH1C
Gene description: alcohol dehydrogenase 1C (class I), gamma polypeptide
See related: BGD:BT11948; Ensembl:ENSBTAG00000034189
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: ADH3
Annotation information: Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	6	NC_037333.1 (25281402..25302044)

Chromosome 6 - NC_037333.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ADH1C c.-64T>C genotype, in combination with reduced vitamin A supplementation, could potentially be implemented in marker-assisted management to maximize marbling in finishing cattle.
Title: The impact of vitamin A restriction and ADH1C genotype on marbling in feedlot steers.
N-acylethanolamines as novel alcohol dehydrogenase 3 substrates.
Title: N-acylethanolamines as novel alcohol dehydrogenase 3 substrates.

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General gene information

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Markers

GDB:187387 (e-PCR)
- UniSTS:155548

RW3 (e-PCR)
- UniSTS:241567

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables all-trans-retinol dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in retinoic acid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in retinol metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alcohol dehydrogenase 1C

Names: alcohol dehydrogenase 1C (class 1), gamma polypeptide; alcohol dehydrogenase 3; alcohol dehydrogenase LOC509744

NP_001193316.1

EC 1.1.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001206387.1 → NP_001193316.1 alcohol dehydrogenase 1C

Status: PROVISIONAL

Source sequence(s)

BC111290, EV732637

UniProtKB/TrEMBL

A0A3Q1M857

Related

ENSBTAP00000056991.2, ENSBTAT00000070693.2

Conserved Domains (2) summary

cd08299
Location:3 → 375

alcohol_DH_class_I_II_IV; class I, II, IV alcohol dehydrogenases

COG1062
Location:8 → 375

FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]