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MRTFA myocardin related transcription factor A [ Bos taurus (domestic cattle) ]

Gene ID: 509011, updated on 4-Oct-2024

Summary

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Official Symbol
MRTFAprovided by VGNC
Official Full Name
myocardin related transcription factor Aprovided by VGNC
Primary source
VGNC:VGNC:55393
See related
BGD:BT23671; Ensembl:ENSBTAG00000002630
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
MKL1
Orthologs
human mouse all
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Genomic context

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See MRTFA in Genome Data Viewer
Location:
chromosome: 5
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (111739967..111916111, complement)

Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene adenylosuccinate lyase Neighboring gene small G protein signaling modulator 3 Neighboring gene microRNA mir-2439 Neighboring gene uncharacterized LOC104972592 Neighboring gene small nucleolar RNA SNORA33

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. β-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition. Charbonney E, et al. Mol Biol Cell, 2011 Dec. PMID 21965288, Free PMC Article
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. beta-catenin controls myocardin-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes.
    Title: β-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in smooth muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
MKL/myocardin-like protein 1; myocardin-related transcription factor A
Names
megakaryoblastic leukemia (translocation) 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    111739967..111916111 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010805772.4 → XP_010804074.1  myocardin-related transcription factor A isoform X2

    See identical proteins and their annotated locations for XP_010804074.1

    UniProtKB/TrEMBL
    A0A3Q1LLJ2
    Related
    ENSBTAP00000060646.1, ENSBTAT00000070929.2
    Conserved Domains (2) summary
    smart00707
    Location:59 → 84
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    pfam02037
    Location:380 → 413
    SAP; SAP domain

  2. XM_005207445.5 → XP_005207502.1  myocardin-related transcription factor A isoform X1

    See identical proteins and their annotated locations for XP_005207502.1

    UniProtKB/TrEMBL
    E1BDD9
    Related
    ENSBTAP00000003407.7, ENSBTAT00000003407.7
    Conserved Domains (2) summary
    smart00707
    Location:113 → 138
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    pfam02037
    Location:434 → 467
    SAP; SAP domain
Nucleotide Protein Strain
Heading Accession and Version

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