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NTM neurotrimin [ Homo sapiens (human) ]

Gene ID: 50863, updated on 7-Apr-2024

Summary

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Official Symbol
NTMprovided by HGNC
Official Full Name
neurotriminprovided by HGNC
Primary source
HGNC:HGNC:17941
See related
Ensembl:ENSG00000182667 MIM:607938; AllianceGenome:HGNC:17941
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HNT; NTRI; CEPU-1; IGLON2
Summary
This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic mechanism. This gene is closely linked to a related family member, opioid binding protein/cell adhesion molecule-like (OPCML), on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]
Expression
Biased expression in brain (RPKM 12.0), lung (RPKM 3.5) and 5 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
11q25
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (131370615..132336822)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (131406501..132375341)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (131240510..132206716)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984412 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5758 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131091329-131091830 Neighboring gene NANOG hESC enhancer GRCh37_chr11:131092980-131093481 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131105841-131106494 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:131115943-131116588 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:131122872-131123374 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:131123375-131123875 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:131124378-131124878 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:131130939-131131476 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:131130399-131130938 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:131126385-131126884 Neighboring gene uncharacterized LOC124902794 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:131211673-131212872 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131243973-131244635 Neighboring gene RNA, U6atac small nuclear 12, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131317907-131318407 Neighboring gene Sharpr-MPRA regulatory region 1894 Neighboring gene uncharacterized LOC101929653 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131454209-131455006 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5759 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:131533266-131533822 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:131540246-131540746 Neighboring gene Sharpr-MPRA regulatory region 15285 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:131547556-131548159 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131551806-131552306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131552307-131552807 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:131550487-131550986 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:131549985-131550486 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4083 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:131560563-131561086 Neighboring gene GPN-loop GTPase 1 pseudogene Neighboring gene NTM antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131707168-131707668 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131707669-131708169 Neighboring gene Sharpr-MPRA regulatory region 14910 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131738361-131738886 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131735724-131736230 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:131737835-131738360 Neighboring gene uncharacterized LOC107984413 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:131758747-131759640 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5760 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4084 Neighboring gene Sharpr-MPRA regulatory region 6145 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:131801564-131801730 Neighboring gene NANOG hESC enhancer GRCh37_chr11:131824673-131825174 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr11:131847321-131847831 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr11:131851053-131852006 Neighboring gene VISTA enhancer hs335 Neighboring gene uncharacterized LOC124902795 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:131958013-131959212 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5761 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:131992888-131993886 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5762 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5763 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132115578-132116078 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132154772-132155340 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132154202-132154771 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5764 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:132188093-132189292 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132199915-132200414 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132204500-132205000 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5765 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:132324306-132324486 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:132340747-132341946 Neighboring gene NTM intronic transcript Neighboring gene uncharacterized LOC124902819 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:132483305-132484504 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:132502505-132503704 Neighboring gene opioid binding protein/cell adhesion molecule like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132513245-132513744 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132551286-132551786 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132551787-132552287 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132755960-132756466 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr11:132780259-132781458 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:132789928-132790505 Neighboring gene uncharacterized LOC105369580

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Steroid hormones and hormone antagonists regulate the neural marker neurotrimin in uterine leiomyoma. Parikh TP, et al. Fertil Steril, 2020 Jan. PMID 32033718
  2. 11q24.2-25 micro-rearrangements in autism spectrum disorders: Relation to brain structures. Maruani A, et al. Am J Med Genet A, 2015 Dec. PMID 26334118
  3. A balanced translocation truncates Neurotrimin in a family with intracranial and thoracic aortic aneurysm. Luukkonen TM, et al. J Med Genet, 2012 Oct. PMID 23054244, Free PMC Article
  4. The cloning and preliminarily functional analysis of the human neurotrimin gene. Liu J, et al. Sci China C Life Sci, 2004 Apr. PMID 15379248
  5. Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes. Venkannagari H, et al. J Mol Biol, 2020 Sep 4. PMID 32710982, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.
    Title: Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes.
  2. Neurotrimin, a neural cell adhesion molecule, is increased in leiomyoma compared to myometrium in patient tissue after estrogen and progesterone treatment.
    Title: Steroid hormones and hormone antagonists regulate the neural marker neurotrimin in uterine leiomyoma.
  3. NTM is not a susceptibility gene for autism spectrum disorders.
    Title: 11q24.2-25 micro-rearrangements in autism spectrum disorders: Relation to brain structures.
  4. Both the AFF3 and NTM triglyceride associations were replicated among Multi-ethnic Study of Atherosclerosis study participants (P = 1.00 x 10(-7) and 8.00 x 10(-5), respectively).
    Title: Genome-wide linkage and positional association analyses identify associations of novel AFF3 and NTM genes with triglycerides: the GenSalt study.
  5. The generation and cardiac phenotype of single and double heterozygous gene-targeted OPCML and Neurotrimin knockout mice.
    Title: Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects.
  6. A translocation breaks intron 1 of a splicing isoform of Neurotrimin at 11q25 in a family with intracranial and thoracic aortic aneurysm.
    Title: A balanced translocation truncates Neurotrimin in a family with intracranial and thoracic aortic aneurysm.
  7. A quantitative analysis of central corneal thickness and a subsequent analysis of primary open-angle glaucoma (POAG), SNPs in two cell adhesion molecules, NTM and CNTNAP4, were identified and may increase POAG susceptibility in a subset of cases.
    Title: Genome-wide analysis of central corneal thickness in primary open-angle glaucoma cases in the NEIGHBOR and GLAUGEN consortia.
  8. The finding of this study provided evidence that NTM at 11q25 chromosome regions affecting IQ.
    Title: NTM and NR3C2 polymorphisms influencing intelligence: family-based association studies.
  9. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
    Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
  10. Observational study of gene-disease association. (HuGE Navigator)
    Title: NTM and NR3C2 polymorphisms influencing intelligence: family-based association studies.
Submit: New GeneRIF Correction See all GeneRIFs (13)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.
EBI GWAS Catalog
Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies.
EBI GWAS Catalog
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
EBI GWAS Catalog
Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
EBI GWAS Catalog
Genome-wide association study identifies candidate genes for male fertility traits in humans.
EBI GWAS Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog
Variants in several genomic regions associated with asperger disorder.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC60329

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
  
involved_in neuron recognition TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region TAS
Traceable Author Statement
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
neurotrimin
Names
IgLON family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048209.2 → NP_001041674.1  neurotrimin isoform 2 precursor

    See identical proteins and their annotated locations for NP_001041674.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and in the coding region compared to variant 3, resulting in a protein that maintains the reading frame but is shorter and has a distinct N-terminus, compared to isoform 3.
    Source sequence(s)
    AA854425, AP004248, AY358331, BE504685
    Consensus CDS
    CCDS41733.1
    UniProtKB/TrEMBL
    B7Z9J9
    Related
    ENSP00000363923.3, ENST00000374791.7
    Conserved Domains (3) summary
    pfam13927
    Location:222 → 299
    Ig_3; Immunoglobulin domain
    cd00096
    Location:223 → 229
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  2. NM_001144058.2 → NP_001137530.1  neurotrimin isoform 3 precursor

    See identical proteins and their annotated locations for NP_001137530.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) encodes isoform 3.
    Source sequence(s)
    AP000844, AP004248, AP005155
    Consensus CDS
    CCDS44777.1
    UniProtKB/TrEMBL
    B7Z9J9
    Related
    ENSP00000396722.2, ENST00000425719.6
    Conserved Domains (3) summary
    smart00409
    Location:233 → 310
    IG; Immunoglobulin
    pfam13927
    Location:136 → 205
    Ig_3; Immunoglobulin domain
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  3. NM_001144059.3 → NP_001137531.1  neurotrimin isoform 4 precursor

    See identical proteins and their annotated locations for NP_001137531.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 3' coding region and 3' UTR compared to variant 3. The resulting protein (isoform 4) has a distinct C-terminus, compared to isoform 3.
    Source sequence(s)
    AP000844, AP004248, AP005155
    Consensus CDS
    CCDS44778.1
    UniProtKB/TrEMBL
    B7Z1H3
    Related
    ENSP00000363916.1, ENST00000374784.5
    Conserved Domains (3) summary
    smart00409
    Location:233 → 310
    IG; Immunoglobulin
    pfam13927
    Location:136 → 205
    Ig_3; Immunoglobulin domain
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  4. NM_001352001.2 → NP_001338930.1  neurotrimin isoform 5 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variant 33, encodes isoform 5.
    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z9J9
    Conserved Domains (3) summary
    pfam13927
    Location:222 → 299
    Ig_3; Immunoglobulin domain
    cd00096
    Location:223 → 229
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  5. NM_001352002.2 → NP_001338931.1  neurotrimin isoform 6 precursor

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z9J9
    Conserved Domains (3) summary
    smart00409
    Location:233 → 310
    IG; Immunoglobulin
    pfam13927
    Location:136 → 205
    Ig_3; Immunoglobulin domain
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  6. NM_001352003.2 → NP_001338932.1  neurotrimin isoform 7 precursor

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z9J9
    Conserved Domains (3) summary
    pfam13927
    Location:222 → 299
    Ig_3; Immunoglobulin domain
    cd00096
    Location:223 → 229
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  7. NM_001352004.2 → NP_001338933.1  neurotrimin isoform 8 precursor

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    smart00409
    Location:233 → 310
    IG; Immunoglobulin
    pfam13927
    Location:136 → 205
    Ig_3; Immunoglobulin domain
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  8. NM_001352005.2 → NP_001338934.1  neurotrimin isoform 9 precursor

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155
    Consensus CDS
    CCDS91626.1
    UniProtKB/TrEMBL
    B7Z1Z5, B7Z9J9
    Related
    ENSP00000507313.1, ENST00000683400.1
    Conserved Domains (3) summary
    pfam13927
    Location:222 → 299
    Ig_3; Immunoglobulin domain
    cd00096
    Location:223 → 229
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

  9. NM_001352006.2 → NP_001338935.1  neurotrimin isoform 10

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003039, AP003166, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1I4, B7Z9J9
    Conserved Domains (3) summary
    smart00409
    Location:224 → 301
    IG; Immunoglobulin
    pfam13927
    Location:127 → 196
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35 → 123
    Ig; Immunoglobulin domain

  10. NM_001352007.2 → NP_001338936.1  neurotrimin isoform 11

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003039, AP003166, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    smart00409
    Location:224 → 301
    IG; Immunoglobulin
    pfam13927
    Location:127 → 196
    Ig_3; Immunoglobulin domain
    cl11960
    Location:35 → 123
    Ig; Immunoglobulin domain

  11. NM_001352008.2 → NP_001338937.1  neurotrimin isoform 12

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    pfam13927
    Location:203 → 280
    Ig_3; Immunoglobulin domain
    cd00096
    Location:204 → 210
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:25 → 113
    Ig; Immunoglobulin domain

  12. NM_001352009.2 → NP_001338938.1  neurotrimin isoform 13

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    pfam13927
    Location:181 → 258
    Ig_3; Immunoglobulin domain
    cd00096
    Location:182 → 188
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:3 → 91
    Ig; Immunoglobulin domain

  13. NM_001386964.1 → NP_001373893.1  neurotrimin isoform 14

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    pfam13927
    Location:208 → 285
    Ig_3; Immunoglobulin domain
    cd00096
    Location:209 → 215
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:3 → 118
    Ig; Immunoglobulin domain

  14. NM_001386965.1 → NP_001373894.1  neurotrimin isoform 15

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    pfam13927
    Location:187 → 264
    Ig_3; Immunoglobulin domain
    cd00096
    Location:188 → 194
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:21 → 97
    Ig; Immunoglobulin domain

  15. NM_001386966.1 → NP_001373895.1  neurotrimin isoform 16

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23), as well as variant 36, encodes isoform 16.
    Source sequence(s)
    AP000844, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    pfam13927
    Location:181 → 258
    Ig_3; Immunoglobulin domain
    cd00096
    Location:182 → 188
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:3 → 91
    Ig; Immunoglobulin domain

  16. NM_001386967.1 → NP_001373896.1  neurotrimin isoform 17

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    pfam13927
    Location:217 → 294
    Ig_3; Immunoglobulin domain
    cd00096
    Location:218 → 224
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:51 → 127
    Ig; Immunoglobulin domain

  17. NM_001386968.1 → NP_001373897.1  neurotrimin isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (33), as well as variant 5, encodes isoform 5.
    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    pfam13927
    Location:181 → 258
    Ig_3; Immunoglobulin domain
    cd00096
    Location:182 → 188
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:3 → 91
    Ig; Immunoglobulin domain

  18. NM_001386969.1 → NP_001373898.1  neurotrimin isoform 16

    Status: REVIEWED

    Description
    Transcript Variant: This variant (36), as well as variant 23, encodes isoform 16.
    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155
    UniProtKB/TrEMBL
    B7Z1H3
    Conserved Domains (3) summary
    pfam13927
    Location:181 → 258
    Ig_3; Immunoglobulin domain
    cd00096
    Location:182 → 188
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:3 → 91
    Ig; Immunoglobulin domain

  19. NM_016522.3 → NP_057606.1  neurotrimin isoform 1 precursor

    See identical proteins and their annotated locations for NP_057606.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) lacks an alternate exon in the 3' coding region, compared to variant 3. This variant encodes isoform 1, which is shorter than isoform 3.
    Source sequence(s)
    AP000844, AP004248, AP005155
    Consensus CDS
    CCDS8491.1
    UniProtKB/Swiss-Prot
    A0MTT2, Q6UXJ3, Q86VJ9, Q9P121
    UniProtKB/TrEMBL
    B7Z1H3
    Related
    ENSP00000363918.1, ENST00000374786.5
    Conserved Domains (3) summary
    pfam13927
    Location:222 → 299
    Ig_3; Immunoglobulin domain
    cd00096
    Location:223 → 229
    Ig; putative Ig strand A [structural motif]
    cl11960
    Location:44 → 132
    Ig; Immunoglobulin domain

RNA

  1. NR_147848.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155

  2. NR_147849.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248

  3. NR_147850.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155

  4. NR_147851.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155

  5. NR_147852.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248

  6. NR_147853.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155

  7. NR_147854.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248

  8. NR_170346.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003039, AP003166, AP004248, AP005155

  9. NR_170347.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155

  10. NR_170348.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP003166, AP004248, AP005155

  11. NR_170349.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248

  12. NR_170350.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP003166, AP004248, AP005155

  13. NR_170351.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003039, AP003166, AP004248, AP005155

  14. NR_170352.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003039, AP003166, AP004248, AP005155

  15. NR_170354.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155

  16. NR_170355.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155

  17. NR_170357.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155

  18. NR_170358.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003039, AP004248, AP005155

  19. NR_170359.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155

  20. NR_170360.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155

  21. NR_170361.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP004248, AP005155

  22. NR_170362.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP004248
    Related
    ENST00000474900.5

  23. NR_170363.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP004248
    Related
    ENST00000539799.5

  24. NR_170364.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP004248

  25. NR_170365.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP004248

  26. NR_170366.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP000844, AP003166, AP004248, AP005155

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    131370615..132336822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    131406501..132375341
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9P121.1 GenPept UniProtKB/Swiss-Prot:Q9P121

Gene LinkOut

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