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JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase [ Bos taurus (domestic cattle) ]

Gene ID: 508343, updated on 10-Oct-2024

Summary

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Official Symbol
JMJD6provided by VGNC
Official Full Name
jumonji domain containing 6, arginine demethylase and lysine hydroxylaseprovided by VGNC
Primary source
VGNC:VGNC:30377
See related
BGD:BT21363; Ensembl:ENSBTAG00000019153
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
PTDSR
Orthologs
human mouse all
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Genomic context

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See JMJD6 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (55052563..55058374)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 11 Neighboring gene serine and arginine rich splicing factor 2 Neighboring gene methyltransferase like 23 Neighboring gene uncharacterized LOC132343117 Neighboring gene matrix remodeling associated 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of Jumonji C-domain containing protein 6 (JMJD6) in infectivity of foot-and-mouth disease virus. Lawrence P, et al. Virology, 2016 May. PMID 26896934
  2. Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: role of Jumonji C-domain containing protein 6 in RHA demethylation. Lawrence P, et al. Virology, 2014 Mar. PMID 24606677
  3. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
  4. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
  5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. JMJD6 contributes to foot-and-mouth disease virus infectivity and may be a previously unidentified foot-and-mouth disease receptor.
    Title: Role of Jumonji C-domain containing protein 6 (JMJD6) in infectivity of foot-and-mouth disease virus.
  2. Demethylated RHA bound JMJD6 monomer during foot-and-mouth disease virus infection.
    Title: Redistribution of demethylated RNA helicase A during foot-and-mouth disease virus infection: role of Jumonji C-domain containing protein 6 in RHA demethylation.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Clone Names

  • MGC128950

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables P-TEFb complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H4R3 demethylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Names
arginine demethylase and lysine hydroxylase
histone arginine demethylase JMJD6
jmjC domain-containing protein 6
jumonji domain-containing protein 6
lysyl-hydroxylase JMJD6
peptide-lysine 5-dioxygenase JMJD6
phosphatidylserine receptor
NP_001029492.2
XP_005221233.1
XP_010814822.1
XP_059733852.1
XP_059733853.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034320.2 → NP_001029492.2  bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

    See identical proteins and their annotated locations for NP_001029492.2

    Status: PROVISIONAL

    Source sequence(s)
    BT021521
    UniProtKB/Swiss-Prot
    Q58DS6
    UniProtKB/TrEMBL
    A0A3Q1MJH5
    Related
    ENSBTAP00000070931.2, ENSBTAT00000083866.2
    Conserved Domains (1) summary
    pfam02373
    Location:174 → 288
    JmjC; JmjC domain, hydroxylase

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    55052563..55058374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059877869.1 → XP_059733852.1  bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X2

  2. XM_005221176.5 → XP_005221233.1  bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X3

    See identical proteins and their annotated locations for XP_005221233.1

    UniProtKB/TrEMBL
    I6L9I1
    Conserved Domains (1) summary
    pfam02373
    Location:174 → 288
    JmjC; JmjC domain, hydroxylase

  3. XM_010816520.4 → XP_010814822.1  bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1

    UniProtKB/TrEMBL
    A0AAA9TV38
    Related
    ENSBTAP00000102483.1, ENSBTAT00000115584.1
    Conserved Domains (1) summary
    pfam02373
    Location:174 → 288
    JmjC; JmjC domain, hydroxylase

  4. XM_059877870.1 → XP_059733853.1  bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X3

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q58DS6.1 GenPept UniProtKB/Swiss-Prot:Q58DS6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials