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U2AF2 U2 small nuclear RNA auxiliary factor 2 [ Bos taurus (domestic cattle) ]

Gene ID: 507895, updated on 4-Oct-2024

Summary

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Official Symbol
U2AF2provided by VGNC
Official Full Name
U2 small nuclear RNA auxiliary factor 2provided by VGNC
Primary source
VGNC:VGNC:36556
See related
BGD:BT28244; Ensembl:ENSBTAG00000002830
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See U2AF2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (61879214..61892236, complement)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene vomeronasal type-1 receptor 4-like Neighboring gene epsin 1 Neighboring gene coiled-coil domain containing 106 Neighboring gene zinc finger protein 581

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. U2AF65 enhances milk synthesis and growth of bovine mammary epithelial cells by positively regulating the mTOR-SREBP-1c signalling pathway. Yu Y, et al. Cell Biochem Funct, 2019 Mar. PMID 30773658
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. U2AF65 functions as a positive regulator of milk synthesis in and proliferation of bovine mammary epithelial cells via the mTOR-SREBP-1c signalling pathway.
    Title: U2AF65 enhances milk synthesis and growth of bovine mammary epithelial cells by positively regulating the mTOR-SREBP-1c signalling pathway.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables poly-pyrimidine tract binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pre-mRNA 3'-splice site binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of U2-type prespliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of U2AF complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of commitment complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
splicing factor U2AF 65 kDa subunit
Names
U2 (RNU2) small nuclear RNA auxiliary factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075336.2 → NP_001068804.1  splicing factor U2AF 65 kDa subunit

    See identical proteins and their annotated locations for NP_001068804.1

    Status: PROVISIONAL

    Source sequence(s)
    BC114160
    UniProtKB/TrEMBL
    A0A3Q1N2I2, G5E532, Q24JZ8
    Conserved Domains (1) summary
    TIGR01642
    Location:63 → 474
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    61879214..61892236 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010815477.3 → XP_010813779.1  splicing factor U2AF 65 kDa subunit isoform X4

    See identical proteins and their annotated locations for XP_010813779.1

    UniProtKB/TrEMBL
    A0A3Q1N2I2
    Conserved Domains (1) summary
    TIGR01642
    Location:4 → 455
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  2. XM_010815476.3 → XP_010813778.1  splicing factor U2AF 65 kDa subunit isoform X3

    See identical proteins and their annotated locations for XP_010813778.1

    UniProtKB/TrEMBL
    A0A3Q1N2I2
    Related
    ENSBTAP00000063486.2, ENSBTAT00000080026.2
    Conserved Domains (1) summary
    TIGR01642
    Location:4 → 459
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  3. XM_005219679.3 → XP_005219736.1  splicing factor U2AF 65 kDa subunit isoform X2

    See identical proteins and their annotated locations for XP_005219736.1

    UniProtKB/TrEMBL
    A0A3Q1N2I2
    Conserved Domains (1) summary
    TIGR01642
    Location:63 → 470
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  4. XM_005219678.3 → XP_005219735.1  splicing factor U2AF 65 kDa subunit isoform X1

    See identical proteins and their annotated locations for XP_005219735.1

    UniProtKB/TrEMBL
    A0A3Q1N2I2, G5E532, Q24JZ8
    Related
    ENSBTAP00000003664.7, ENSBTAT00000003664.7
    Conserved Domains (1) summary
    TIGR01642
    Location:63 → 474
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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