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DOCK5 dedicator of cytokinesis 5 [ Bos taurus (domestic cattle) ]

Gene ID: 505572, updated on 10-Oct-2024

Summary

Official Symbol
DOCK5provided by VGNC
Official Full Name
dedicator of cytokinesis 5provided by VGNC
Primary source
VGNC:VGNC:28159
See related
BGD:BT17514; Ensembl:ENSBTAG00000015513
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See DOCK5 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
53
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 8 NC_037335.1 (72443588..72724236)

Chromosome 8 - NC_037335.1Genomic Context describing neighboring genes Neighboring gene neurofilament light chain Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC100335268 Neighboring gene microRNA mir-2285ae Neighboring gene uncharacterized LOC112447820 Neighboring gene gonadotropin releasing hormone 1 Neighboring gene potassium channel tetramerization domain containing 9

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037335.1 Chromosome 8 Reference ARS-UCD2.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
dedicator of cytokinesis protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037335.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    72443588..72724236
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005210292.5XP_005210349.1  dedicator of cytokinesis protein 5 isoform X1

    See identical proteins and their annotated locations for XP_005210349.1

    UniProtKB/TrEMBL
    A0A3Q1MC59, F1MJ73
    Related
    ENSBTAP00000020616.5, ENSBTAT00000020616.6
    Conserved Domains (4) summary
    cd11708
    Location:12381637
    DHR2_DOCK5; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 5
    cd12051
    Location:1267
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:71434
    DOCK_N; DOCK N-terminus
    cl14603
    Location:442637
    C2; C2 domain
  2. XM_010808067.4XP_010806369.1  dedicator of cytokinesis protein 5 isoform X2

    See identical proteins and their annotated locations for XP_010806369.1

    UniProtKB/TrEMBL
    A0A3Q1MC59, A0A3Q1MFA9
    Related
    ENSBTAP00000067610.1, ENSBTAT00000071204.2
    Conserved Domains (4) summary
    cd11708
    Location:12061605
    DHR2_DOCK5; Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 5
    cd12051
    Location:1267
    SH3_DOCK1_5_A; Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5
    pfam16172
    Location:71434
    DOCK_N; DOCK N-terminus
    cl14603
    Location:442637
    C2; C2 domain
  3. XM_059889493.1XP_059745476.1  dedicator of cytokinesis protein 5 isoform X4

  4. XM_059889492.1XP_059745475.1  dedicator of cytokinesis protein 5 isoform X3