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MCM4 minichromosome maintenance complex component 4 [ Bos taurus (domestic cattle) ]

Gene ID: 504367, updated on 4-Oct-2024

Summary

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Official Symbol
MCM4provided by VGNC
Official Full Name
minichromosome maintenance complex component 4provided by VGNC
Primary source
VGNC:VGNC:106815
See related
BGD:BT25424; Ensembl:ENSBTAG00000017021
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See MCM4 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (19551825..19563217)

Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene H3 histone, family 3C Neighboring gene protein kinase, DNA-activated, catalytic subunit Neighboring gene nucleolar RNA helicase 2-like Neighboring gene ubiquitin conjugating enzyme E2 V2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC138087, MGC140484

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA strand elongation involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via break-induced replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MCM complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA replication licensing factor MCM4
Names
MCM4 minichromosome maintenance deficient 4
NP_001068626.1
XP_024857211.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075158.1 → NP_001068626.1  DNA replication licensing factor MCM4

    See identical proteins and their annotated locations for NP_001068626.1

    Status: PROVISIONAL

    Source sequence(s)
    BC118099
    UniProtKB/TrEMBL
    E1BFZ9, Q148N1
    Related
    ENSBTAP00000049149.4, ENSBTAT00000054380.4
    Conserved Domains (4) summary
    cd00009
    Location:478 → 623
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    smart00350
    Location:240 → 743
    MCM; minichromosome maintenance proteins
    pfam11679
    Location:4 → 47
    DUF3275; Protein of unknown function (DUF3275)
    pfam14551
    Location:139 → 260
    MCM_N; MCM N-terminal domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    19551825..19563217
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025001443.2 → XP_024857211.1  DNA replication licensing factor MCM4 isoform X1

    UniProtKB/TrEMBL
    E1BFZ9
    Related
    ENSBTAP00000079802.1, ENSBTAT00000122009.1
    Conserved Domains (3) summary
    smart00350
    Location:240 → 743
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:139 → 237
    MCM_N; MCM N-terminal domain
    cl28034
    Location:3 → 145
    Herpes_ICP4_N; Herpesvirus ICP4-like protein N-terminal region
Nucleotide Protein Strain
Heading Accession and Version

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