bmp6 bone morphogenetic protein 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bmp6provided by ZNC
Official Full Name: bone morphogenetic protein 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-050306-42
See related: Ensembl:ENSDARG00000015686 AllianceGenome:ZFIN:ZDB-GENE-050306-42
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:113595
Summary: Predicted to enable cytokine activity. Acts upstream of or within bone morphogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including choroidal fissure; ectoderm; epidermis; fin; and ventral mesoderm. Orthologous to human BMP6 (bone morphogenetic protein 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (7861373..7935802)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (7832054..7906483)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cytokine activity	IBA Inferred from Biological aspect of Ancestor more info
enables growth factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in BMP signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within bone morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: bone morphogenetic protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013339.1 → NP_001013357.1 bone morphogenetic protein 6 precursor

See identical proteins and their annotated locations for NP_001013357.1

Status: PROVISIONAL

Source sequence(s)

BC090689

UniProtKB/TrEMBL

Q5CZV5

Related

ENSDARP00000022649.5, ENSDART00000019705.7

Conserved Domains (2) summary

smart00204
Location:316 → 417

TGFB; Transforming growth factor-beta (TGF-beta) family

pfam00688
Location:28 → 267

TGFb_propeptide; TGF-beta propeptide