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CG32354 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50302, updated on 18-Sep-2024

Summary

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Official Symbol
CG32354provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052354
Locus tag
Dmel_CG32354
See related
AllianceGenome:FB:FBgn0052354
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:CK01670; CG17355; CG7027; CG7159; CK01670; Dmel\CG32354
Summary
Predicted to be involved in cell differentiation. Is expressed in embryonic/larval nervous system; extended germ band embryo; presumptive embryonic/larval system; and ventral midline of embryo. Human ortholog(s) of this gene implicated in polycystic ovary syndrome. Orthologous to human FST (follistatin). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG32354 in Genome Data Viewer
Location:
66C11-66C12; 3-24 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8415857..8422205, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8408957..8415305, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Outer segment 1 Neighboring gene Exocyst 70 Neighboring gene matrimony Neighboring gene Cbl proto-oncogene Neighboring gene Upstream of N-ras

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A deficiency screen of the major autosomes identifies a gene (matrimony) that is haplo-insufficient for achiasmate segregation in Drosophila oocytes. Harris D, et al. Genetics, 2003 Oct. PMID 14573476, Free PMC Article
  2. A high throughput screen to identify secreted and transmembrane proteins involved in Drosophila embryogenesis. Kopczynski CC, et al. Proc Natl Acad Sci U S A, 1998 Aug 18. PMID 9707585, Free PMC Article
  3. Spitz from the retina regulates genes transcribed in the second mitotic wave, peripodial epithelium, glia and plasmatocytes of the Drosophila eye imaginal disc. Firth LC, et al. Dev Biol, 2007 Jul 15. PMID 17553483, Free PMC Article
  4. Gene expression during Drosophila wing morphogenesis and differentiation. Ren N, et al. Genetics, 2005 Oct. PMID 15998724, Free PMC Article
  5. Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization. Menoret D, et al. Genome Biol, 2013 Aug 23. PMID 23972280, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG32354-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    8415857..8422205 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168275.2 → NP_729380.1  uncharacterized protein Dmel_CG32354 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729380.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95U40, Q9VSK1
    Related
    FBpp0076385
    Conserved Domains (2) summary
    smart00280
    Location:606 → 650
    KAZAL; Kazal type serine protease inhibitors
    cl00097
    Location:163 → 200
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VSK1 Q9VSK1

Gene LinkOut

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