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Tbc1d22b TBC1 domain family, member 22B [ Rattus norvegicus (Norway rat) ]

Gene ID: 502414, updated on 17-Aug-2024

Summary

Official Symbol
Tbc1d22bprovided by RGD
Official Full Name
TBC1 domain family, member 22Bprovided by RGD
Primary source
RGD:1564987
See related
EnsemblRapid:ENSRNOG00000059458 AllianceGenome:RGD:1564987
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable 14-3-3 protein binding activity. Orthologous to human TBC1D22B (TBC1 domain family member 22B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 43.5), Spleen (RPKM 41.1) and 9 other tissues See more
Orthologs
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Genomic context

See Tbc1d22b in Genome Data Viewer
Location:
20p12
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (7620716..7676809)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (7619096..7675232)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (8216097..8278344)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene RAN, member RAS oncogene family, pseudogene 5 Neighboring gene transmembrane protein 217B Neighboring gene transmembrane protein 217 Neighboring gene ring finger protein 8 Neighboring gene cap methyltransferase 1 Neighboring gene coiled-coil domain containing 167

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
TBC1 domain family member 22B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025059.1NP_001020230.1  TBC1 domain family member 22B

    See identical proteins and their annotated locations for NP_001020230.1

    Status: PROVISIONAL

    Source sequence(s)
    AY380821
    UniProtKB/TrEMBL
    A0A8I5ZVI8, A0A8I5ZW76, A6JJV3, Q6U1J1
    Related
    ENSRNOP00000083239.1, ENSRNOT00000093855.2
    Conserved Domains (1) summary
    smart00164
    Location:207457
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    7620716..7676809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005497331.2 RNA Sequence