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Vwa3b von Willebrand factor A domain containing 3B [ Rattus norvegicus (Norway rat) ]

Gene ID: 501126, updated on 2-Nov-2024

Summary

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Official Symbol
Vwa3bprovided by RGD
Official Full Name
von Willebrand factor A domain containing 3Bprovided by RGD
Primary source
RGD:1562560
See related
EnsemblRapid:ENSRNOG00000023566 AllianceGenome:RGD:1562560
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 22. Orthologous to human VWA3B (von Willebrand factor A domain containing 3B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 174.8), Lung (RPKM 13.4) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Vwa3b in Genome Data Viewer
Location:
9q21
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (46746307..46915436)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (39249523..39419614)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (43607066..43779466)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene zeta chain of T cell receptor associated protein kinase 70 Neighboring gene transmembrane protein 131 Neighboring gene uncharacterized LOC134480356 Neighboring gene transfer RNA alanine (anticodon AGC) 41 Neighboring gene uncharacterized LOC102554996 Neighboring gene uncharacterized LOC134480357 Neighboring gene cyclic nucleotide gated channel subunit alpha 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC156769

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
von Willebrand factor A domain-containing protein 3B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419961.1 → NP_001406890.1  von Willebrand factor A domain-containing protein 3B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    Related
    ENSRNOP00000079290.2, ENSRNOT00000101179.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    46746307..46915436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039084535.2 → XP_038940463.1  von Willebrand factor A domain-containing protein 3B isoform X4

    Conserved Domains (1) summary
    cd00198
    Location:511 → 656
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  2. XM_063267598.1 → XP_063123668.1  von Willebrand factor A domain-containing protein 3B isoform X2

    Related
    ENSRNOP00000088328.2, ENSRNOT00000023617.7

  3. XM_063267599.1 → XP_063123669.1  von Willebrand factor A domain-containing protein 3B isoform X3

  4. XM_063267597.1 → XP_063123667.1  von Willebrand factor A domain-containing protein 3B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZKI0
    Related
    ENSRNOP00000078235.1, ENSRNOT00000088239.3

RNA

  1. XR_010054626.1 RNA Sequence

  2. XR_010054627.1 RNA Sequence

  3. XR_594349.4 RNA Sequence

  4. XR_001839791.3 RNA Sequence

  5. XR_005489105.2 RNA Sequence

  6. XR_001839789.3 RNA Sequence

  7. XR_010054625.1 RNA Sequence

  8. XR_005489106.2 RNA Sequence

  9. XR_005489107.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001024362.1: Suppressed sequence

    Description
    NM_001024362.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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