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CAH5 Carbonic anhydrase 5 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 50102, updated on 2-Nov-2024

Summary

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Official Symbol
CAH5provided by FlyBase
Official Full Name
Carbonic anhydrase 5provided by FlyBase
Primary source
FLYBASE:FBgn0040629
Locus tag
Dmel_CG18673
See related
AllianceGenome:FB:FBgn0040629
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG18673; Dmel\CG18673
Summary
Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be active in cytoplasm. Is expressed in testis. Orthologous to human CA6 (carbonic anhydrase 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See CAH5 in Genome Data Viewer
Location:
100B9-100B9; 3-102 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31262598..31263878)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27088320..27089600)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Carbonic anhydrase 6 Neighboring gene Carbonic anhydrase 16 Neighboring gene pickpocket 24 Neighboring gene pH-sensitive chloride channel 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Carbonic anhydrases and anion transport in mosquito midgut pH regulation. Linser PJ, et al. J Exp Biol, 2009 Jun. PMID 19448076, Free PMC Article
  2. tBRD-1 and tBRD-2 regulate expression of genes necessary for spermatid differentiation. Theofel I, et al. Biol Open, 2017 Apr 15. PMID 28235844, Free PMC Article
  3. A mitochondrial ATP synthase subunit interacts with TOR signaling to modulate protein homeostasis and lifespan in Drosophila. Sun X, et al. Cell Rep, 2014 Sep 25. PMID 25220459, Free PMC Article
  4. tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family. Theofel I, et al. PLoS One, 2014. PMID 25251222, Free PMC Article
  5. Quercetin ameliorates Aβ toxicity in Drosophila AD model by modulating cell cycle-related protein expression. Kong Y, et al. Oncotarget, 2016 Oct 18. PMID 27626494, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbonate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in one-carbon metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
carbonic anhydrase 5
Names
CAH5-PC
CG18673-PC
NP_001097988.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    31262598..31263878
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001104518.3 → NP_001097988.2  carbonic anhydrase 5 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097988.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V9Y6
    Conserved Domains (1) summary
    smart01057
    Location:43 → 294
    Carb_anhydrase; Eukaryotic-type carbonic anhydrase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V9Y6 Q9V9Y6

Gene LinkOut

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