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Cyp4f17 cytochrome P450, family 4, subfamily f, polypeptide 17 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500801, updated on 14-Nov-2024

Summary

Official Symbol
Cyp4f17provided by RGD
Official Full Name
cytochrome P450, family 4, subfamily f, polypeptide 17provided by RGD
Primary source
RGD:1561655
See related
EnsemblRapid:ENSRNOG00000029478 AllianceGenome:RGD:1561655
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561655
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be involved in small molecule metabolic process. Predicted to be located in endoplasmic reticulum and membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 27.3), Adrenal (RPKM 25.0) and 9 other tissues See more
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Genomic context

See Cyp4f17 in Genome Data Viewer
Location:
7q11
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (12169366..12186731)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (11518985..11536208)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (14527797..14545775) , (14550167..14551959)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene peptidoglycan recognition protein 2 Neighboring gene uncharacterized LOC134479822 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 39 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 5 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 37

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in small molecule metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cytochrome P450, family 4, subfamily f, polypeptide 17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191986.1NP_001178915.1  cytochrome P450, family 4, subfamily f, polypeptide 17

    See identical proteins and their annotated locations for NP_001178915.1

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    A0A8J8Y394, D4AB65
    Conserved Domains (1) summary
    pfam00067
    Location:52514
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    12169366..12186731
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063264097.1XP_063120167.1  cytochrome P450, family 4, subfamily f, polypeptide 17 isoform X2

  2. XM_006241085.5XP_006241147.1  cytochrome P450, family 4, subfamily f, polypeptide 17 isoform X1

    See identical proteins and their annotated locations for XP_006241147.1

    UniProtKB/TrEMBL
    A0A8J8Y394, D4AB65
    Related
    ENSRNOP00000057034.2, ENSRNOT00000060284.6
    Conserved Domains (1) summary
    pfam00067
    Location:52514
    p450; Cytochrome P450