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Lrriq3 leucine-rich repeats and IQ motif containing 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499732, updated on 2-Nov-2024

Summary

Official Symbol
Lrriq3provided by RGD
Official Full Name
leucine-rich repeats and IQ motif containing 3provided by RGD
Primary source
RGD:1591943
See related
EnsemblRapid:ENSRNOG00000009555 AllianceGenome:RGD:1591943
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Lrrc44
Summary
Orthologous to human LRRIQ3 (leucine rich repeats and IQ motif containing 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 314.3) and Spleen (RPKM 13.2) See more
Orthologs
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Genomic context

See Lrriq3 in Genome Data Viewer
Location:
2q45
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (246778759..246871284)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (244119975..244214590)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (261403040..261499893)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta, pseudogene 3 Neighboring gene TNNI3 interacting kinase Neighboring gene leucine rich repeat containing 53 Neighboring gene uncharacterized LOC134486009 Neighboring gene fucose-1-phosphate guanylyltransferase Neighboring gene ribosomal protein L32, pseudogene 7 Neighboring gene uncharacterized LOC134485698

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
leucine-rich repeat and IQ domain-containing protein 3
Names
leucine rich repeat containing 44
leucine-rich repeat-containing protein 44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024307.1NP_001019478.1  leucine-rich repeat and IQ domain-containing protein 3

    See identical proteins and their annotated locations for NP_001019478.1

    Status: PROVISIONAL

    Source sequence(s)
    BC078994
    UniProtKB/Swiss-Prot
    Q6AYL8
    UniProtKB/TrEMBL
    A6HWR0
    Related
    ENSRNOP00000012841.5, ENSRNOT00000012841.9
    Conserved Domains (3) summary
    sd00031
    Location:5273
    LRR_1; leucine-rich repeat [structural motif]
    pfam17380
    Location:388586
    DUF5401; Family of unknown function (DUF5401)
    cd21340
    Location:36128
    PPP1R42; protein phosphatase 1 regulatory subunit 42

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    246778759..246871284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063282410.1XP_063138480.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X3

    Related
    ENSRNOP00000097180.1, ENSRNOT00000095686.2
  2. XM_039102961.2XP_038958889.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A8I5ZK36, A6HWR2
    Related
    ENSRNOP00000076522.1, ENSRNOT00000109356.2
    Conserved Domains (2) summary
    sd00031
    Location:5273
    LRR_1; leucine-rich repeat [structural motif]
    cd21340
    Location:36128
    PPP1R42; protein phosphatase 1 regulatory subunit 42
  3. XM_039102959.2XP_038958887.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X2

  4. XM_063282409.1XP_063138479.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X1