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Apobr apolipoprotein B receptor [ Rattus norvegicus (Norway rat) ]

Gene ID: 499264, updated on 18-Sep-2024

Summary

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Official Symbol
Apobrprovided by RGD
Official Full Name
apolipoprotein B receptorprovided by RGD
Primary source
RGD:1565169
See related
EnsemblRapid:ENSRNOG00000017403 AllianceGenome:RGD:1565169
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Apob48r; RGD1565169
Summary
Predicted to enable very-low-density lipoprotein particle receptor activity. Predicted to be involved in triglyceride metabolic process. Orthologous to human APOBR (apolipoprotein B receptor). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 49.2), Lung (RPKM 35.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Apobr in Genome Data Viewer
Location:
1q36
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (190599595..190603782)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (181169019..181173206)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (197999209..198003839)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3, subunit C Neighboring gene U6 spliceosomal RNA Neighboring gene CLN3 lysosomal/endosomal transmembrane protein, battenin Neighboring gene interleukin 27 Neighboring gene RNA, U2 small nuclear 62 Neighboring gene ribosomal protein L36A, pseudogene 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The murine macrophage apoB-48 receptor gene (Apob-48r): homology to the human receptor. Brown ML, et al. J Lipid Res, 2002 Aug. PMID 12177162
  2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables apolipoprotein receptor activity ISO
Inferred from Sequence Orthology
more info
  
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
enables very-low-density lipoprotein particle receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables very-low-density lipoprotein particle receptor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in triglyceride metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within triglyceride metabolic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
apolipoprotein B receptor
Names
apolipoprotein B-100 receptor
apolipoprotein B48 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001395126.1 → NP_001382055.1  apolipoprotein B receptor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A0A0G2K7M4, A6I994
    Related
    ENSRNOP00000074267.1, ENSRNOT00000091065.3
    Conserved Domains (1) summary
    PTZ00121
    Location:314 → 812
    PTZ00121; MAEBL; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    190599595..190603782
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001109154.1: Suppressed sequence

    Description
    NM_001109154.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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