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Cby2 chibby family member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498572, updated on 10-Jul-2024

Summary

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Official Symbol
Cby2provided by RGD
Official Full Name
chibby family member 2provided by RGD
Primary source
RGD:1561044
See related
EnsemblRapid:ENSRNOG00000047413 AllianceGenome:RGD:1561044
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Spert
Summary
Predicted to enable identical protein binding activity. Predicted to be located in cytoplasmic vesicle. Orthologous to human CBY2 (chibby family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 173.6) and Muscle (RPKM 5.3) See more
Orthologs
human mouse all
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Genomic context

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See Cby2 in Genome Data Viewer
Location:
15q11
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (57318820..57413687, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (50909435..51004449, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (57642576..57738383, complement)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH type containing 13 Neighboring gene uncharacterized LOC120097040 Neighboring gene siah E3 ubiquitin protein ligase family member 3 Neighboring gene GABA type A receptor associated protein like 2, pseudogene 2 Neighboring gene glutamate-rich 6B Neighboring gene component of oligomeric golgi complex 3 Neighboring gene solute carrier family 25, member 30 Neighboring gene uncharacterized LOC102552389

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Nurit, a novel leucine-zipper protein, expressed uniquely in the spermatid flower-like structure. Feige E, et al. Mech Dev, 2002 Sep. PMID 12204287
  2. Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Yachie N, et al. Mol Syst Biol, 2016 Apr 22. PMID 27107012, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein chibby homolog 2
Names
spermatid associated
spermatid-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017506.1 → NP_001017506.1  protein chibby homolog 2

    See identical proteins and their annotated locations for NP_001017506.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079300
    UniProtKB/Swiss-Prot
    Q6AXV6
    UniProtKB/TrEMBL
    A6HTT1
    Related
    ENSRNOP00000083970.2, ENSRNOT00000098900.2
    Conserved Domains (2) summary
    cd07429
    Location:76 → 191
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins
    cl12007
    Location:366 → 425
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    57318820..57413687 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008770895.3 → XP_008769117.1  protein chibby homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_008769117.1

    UniProtKB/TrEMBL
    A0A8I6G3C8, A6HTT1
    Related
    ENSRNOP00000066296.2, ENSRNOT00000072138.3
    Conserved Domains (2) summary
    cd07429
    Location:61 → 176
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins
    cl12007
    Location:351 → 410
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins

  2. XM_008770893.4 → XP_008769115.1  protein chibby homolog 2 isoform X1

    See identical proteins and their annotated locations for XP_008769115.1

    UniProtKB/TrEMBL
    A0A8I6G3C8, A6HTT1
    Conserved Domains (2) summary
    cd07429
    Location:61 → 176
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins
    cl12007
    Location:351 → 410
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins

  3. XM_006252329.4 → XP_006252391.1  protein chibby homolog 2 isoform X3

    UniProtKB/TrEMBL
    A6HTT1
    Conserved Domains (1) summary
    cl12007
    Location:1 → 116
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins

  4. XM_006252328.5 → XP_006252390.1  protein chibby homolog 2 isoform X2

    See identical proteins and their annotated locations for XP_006252390.1

    UniProtKB/TrEMBL
    A0A8I5ZY42, A6HTT0, A6HTT1
    Conserved Domains (2) summary
    cd07429
    Location:40 → 155
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins
    cl12007
    Location:330 → 389
    Cby_like; Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6AXV6.1 GenPept UniProtKB/Swiss-Prot:Q6AXV6

Gene LinkOut

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