U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fcgr2al1 Fc gamma receptor 2A like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498276, updated on 28-Oct-2024

Summary

Go to the top of the page Help
Official Symbol
Fcgr2al1provided by RGD
Official Full Name
Fc gamma receptor 2A like 1provided by RGD
Primary source
RGD:1594388
See related
EnsemblRapid:ENSRNOG00000058500 AllianceGenome:RGD:1594388
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in Fc-gamma receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc gamma receptor IIa) and FCGR2B (Fc gamma receptor IIb). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Lung (RPKM 321.3), Spleen (RPKM 191.9) and 9 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Fcgr2al1 in Genome Data Viewer
Location:
13q24
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (85835616..85846011, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (83302874..83315744, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (91168972..91181937, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene Fc gamma receptor 2A Neighboring gene transfer RNA aspartic acid (anticodon GUC) 10 Neighboring gene transfer RNA leucine (anticodon CAG) 4 Neighboring gene transfer RNA aspartic acid (anticodon GUC) 11 Neighboring gene transfer RNA leucine (anticodon CAG) 5

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Rat CD16 is defined by a family of class III Fc gamma receptors requiring co-expression of heteroprotein subunits. Farber DL, et al. J Immunol, 1991 Jun 15. PMID 1710249
  2. Characterization and expression of an Fc gamma receptor cDNA cloned from rat natural killer cells. Zeger DL, et al. Proc Natl Acad Sci U S A, 1990 May. PMID 1692135, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Fc-gamma receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Fc gamma receptor 2A like 1
Names
Fc gamma receptor II beta
Fc-gamma RIIIB-alpha
Fc-gamma RIIIC-alpha
Fc-gamma RIIID-alpha
low affinity immunoglobulin gamma Fc region receptor III-like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135992.1 → NP_001129464.1  Fc gamma receptor 2A like 1

    See identical proteins and their annotated locations for NP_001129464.1

    Status: PROVISIONAL

    Source sequence(s)
    BC159405
    UniProtKB/TrEMBL
    A0A096MIU6, A0A0G2KB71, B0K007, M0R4F7
    Conserved Domains (3) summary
    cd00096
    Location:42 → 45
    Ig; Ig strand A [structural motif]
    cd05753
    Location:123 → 205
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
    cl11960
    Location:41 → 119
    Ig; Immunoglobulin domain

  2. NM_001430400.1 → NP_001417329.1  Fc gamma receptor 2A like 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013
    UniProtKB/TrEMBL
    A0A096MIU6, B0K007, M0R4F7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    85835616..85846011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039090977.2 → XP_038946905.1  Fc gamma receptor 2A like 1 isoform X2

    UniProtKB/TrEMBL
    A0A0G2KB71
    Related
    ENSRNOP00000069409.3, ENSRNOT00000084881.3
    Conserved Domains (3) summary
    cd00096
    Location:35 → 38
    Ig; Ig strand A [structural motif]
    cd05753
    Location:116 → 198
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
    cl11960
    Location:34 → 112
    Ig; Immunoglobulin domain

  2. XM_039090980.2 → XP_038946908.1  Fc gamma receptor 2A like 1 isoform X4

    Conserved Domains (2) summary
    cd00096
    Location:42 → 45
    Ig; Ig strand A [structural motif]
    cl11960
    Location:41 → 119
    Ig; Immunoglobulin domain

  3. XM_063272543.1 → XP_063128613.1  Fc gamma receptor 2A like 1 isoform X1

  4. XM_039090979.2 → XP_038946907.1  Fc gamma receptor 2A like 1 isoform X3

    Conserved Domains (3) summary
    cd00096
    Location:42 → 45
    Ig; Ig strand A [structural motif]
    cd05753
    Location:123 → 205
    Ig2_FcgammaR_like; Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs), and similar domains
    cl11960
    Location:41 → 119
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.