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gsdA glucose-6-phosphat 1-dehydrogenase gsdA-Aspergillus niger [ Aspergillus niger ]

Gene ID: 4979751, updated on 31-Oct-2024

Summary

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Gene symbol
gsdA
Gene description
glucose-6-phosphat 1-dehydrogenase gsdA-Aspergillus niger
Locus tag
An02g12140
See related
FungiDB:An02g12140; VEuPathDB:An02g12140
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Aspergillus niger
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus subgen. Circumdati
Orthologs
Aspergillus fumigatus all
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Genomic context

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See gsdA in Genome Data Viewer
Location:
chromosome: IV, map: unlocalized, clone: An02
Exon count:
10

NT_166519.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NT_166519.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88. Pel HJ, et al. Nat Biotechnol, 2007 Feb. PMID 17259976
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glucose-6-phosphate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pentose-phosphate shunt, oxidative branch IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glucose-6-phosphat 1-dehydrogenase gsdA-Aspergillus niger
XP_001400342.1
  • Catalytic activity: gsdA of A. niger converts glucose-6-phosphate + NADP(+) = D-glucono-delta-lactone 6-phosphate + NADPH.;
    Function: gsdA of A. niger catalyses the first step in the pentose phosphate pathway.;
    Gene-ID: gsdA;
    Phenotype: overexpression of gsdA in A. niger was shown to be deleterious for the fungus, especially when cotransformants were grown on media containing ammonia.;
    Remark: the predicted ORF overlaps with A. niger ESTs EMBLEST:BE760650, EMBL:ANG6PDHSE (A. niger mRNA for glucose-6-phosphate dehydrogenase) and EMBL:ANNGSDA (A. niger gsdA gene).;
    Repression: glucose-6-phosphat 1-dehydrogenase is inhibited by NADPH and stimulated by NADP(+).;
    cytoplasm

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_166519.1 Reference assembly

    Range
    2953468..2955831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001400305.3 → XP_001400342.1  glucose-6-phosphat 1-dehydrogenase gsdA-Aspergillus niger [Aspergillus niger]

    See identical proteins and their annotated locations for XP_001400342.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P48826
    UniProtKB/TrEMBL
    A0A319ALE5, A0A370C851, A0A3F3RHX8, A0A505I6K0, A2QET1, G3Y226
    Conserved Domains (1) summary
    TIGR00871
    Location:21 → 495
    zwf; glucose-6-phosphate 1-dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48826.1

Gene LinkOut

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Molecular Biology Databases
Research Materials