U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

kntc1 kinetochore associated 1 [ Danio rerio (zebrafish) ]

Gene ID: 497376, updated on 12-Sep-2024

Summary

Official Symbol
kntc1provided by ZNC
Official Full Name
kinetochore associated 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-050208-92
See related
Ensembl:ENSDARG00000101670 AllianceGenome:ZFIN:ZDB-GENE-050208-92
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:6912223; im:7138629
Summary
Predicted to enable small GTPase binding activity. Predicted to be involved in mitotic sister chromatid segregation; mitotic spindle assembly checkpoint signaling; and protein localization to kinetochore involved in kinetochore assembly. Predicted to be part of RZZ complex. Predicted to be active in cytoplasm and kinetochore microtubule. Orthologous to human KNTC1 (kinetochore associated 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See kntc1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
60
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (66433373..66512522)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (65754179..65833414)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene embigin Neighboring gene huntingtin interacting protein 1 related b Neighboring gene uncharacterized LOC110439837 Neighboring gene uncharacterized LOC137495536

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in mitotic sister chromatid segregation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitotic spindle assembly checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein localization to kinetochore involved in kinetochore assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of RZZ complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in kinetochore microtubule IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
kinetochore-associated protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    66433373..66512522
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476680.2XP_021332355.1  kinetochore-associated protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A0R4IHW6, A0A8M9QEY6
    Conserved Domains (1) summary
    pfam10493
    Location:15882135
    Rod_C; Rough deal protein C-terminal region
  2. XM_009301982.4XP_009300257.2  kinetochore-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A0R4IHW6, A0A8M3B017
    Related
    ENSDARP00000133225.1, ENSDART00000170757.2
    Conserved Domains (1) summary
    pfam10493
    Location:15972144
    Rod_C; Rough deal protein C-terminal region
  3. XM_068221568.1XP_068077669.1  kinetochore-associated protein 1 isoform X3

  4. XM_009301984.4XP_009300259.2  kinetochore-associated protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A0R4IHW6, A0A8M3ASW0
    Conserved Domains (1) summary
    pfam10493
    Location:15962143
    Rod_C; Rough deal protein C-terminal region