eif2b2 eukaryotic translation initiation factor 2B subunit beta [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: eif2b2provided by Xenbase
Official Full Name: eukaryotic translation initiation factor 2B subunit betaprovided by Xenbase
Primary source: Xenbase:XB-GENE-974089
See related: Ensembl:ENSXETG00000013261 AllianceGenome:Xenbase:XB-GENE-974089
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable translation initiation factor activity. Predicted to act upstream of or within translational initiation. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter and leukoencephalopathy with vanishing white matter 2. Orthologous to human EIF2B2 (eukaryotic translation initiation factor 2B subunit beta). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (82211297..82215575)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	8	NC_030684.1 (61065265..61069538)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within translational initiation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: translation initiation factor eIF2B subunit beta

Names: eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001171515.1 → NP_001164986.1 translation initiation factor eIF2B subunit beta

See identical proteins and their annotated locations for NP_001164986.1

Status: PROVISIONAL

Source sequence(s)

BC157190

UniProtKB/TrEMBL

A0A803KIJ5, A9ULB2

Related

ENSXETP00000029031.5, ENSXETT00000029031.5

Conserved Domains (2) summary

COG1184
Location:13 → 344

GCD2; Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]

pfam01008
Location:31 → 333

IF-2B; Initiation factor 2 subunit family