thbs3 thrombospondin 3 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: thbs3provided by Xenbase
Official Full Name: thrombospondin 3provided by Xenbase
Primary source: Xenbase:XB-GENE-5761978
See related: Ensembl:ENSXETG00000006338
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: tsp-3
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (146097711..146122884, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	Unplaced Scaffold	NW_016684749.1 (2728..24005)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables heparin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: thrombospondin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001011401.1 → NP_001011401.1 thrombospondin-3 precursor

See identical proteins and their annotated locations for NP_001011401.1

Status: PROVISIONAL

Source sequence(s)

BC088610

UniProtKB/TrEMBL

A0A6I8R4P1, A0A6I8S900, Q5M7J5

Related

ENSXETP00000089136.2, ENSXETT00000078760.2

Conserved Domains (9) summary

cd00054
Location:319 → 355

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

sd00001
Location:613 → 650

TSP3; TSP3 repeat_long [structural motif]

sd00002
Location:495 → 530

TSP3; TSP3 repeat_long [structural motif]

cd16079
Location:230 → 272

TSP-3cc; Coiled coil region of thrombospondin-3 (TSP-3)

pfam02412
Location:554 → 589

TSP_3; Thrombospondin type 3 repeat

pfam05735
Location:744 → 941

TSP_C; Thrombospondin C-terminal region

pfam12947
Location:381 → 410

EGF_3; EGF domain

NF000535
Location:461 → 662

MSCRAMM_SdrC; MSCRAMM family adhesin SdrC

cl22861
Location:58 → 196

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...