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npl N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 496638, updated on 4-Nov-2024

Summary

Official Symbol
nplprovided by Xenbase
Official Full Name
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)provided by Xenbase
Primary source
Xenbase:XB-GENE-978364
See related
Ensembl:ENSXETG00000012514 AllianceGenome:Xenbase:XB-GENE-978364
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
c112; npl1; npl-a; npl-b; dhdps1
Summary
Predicted to enable N-acetylneuraminate lyase activity. Predicted to be involved in N-acetylneuraminate catabolic process. Predicted to be located in cytoplasm. Orthologous to human NPL (N-acetylneuraminate pyruvate lyase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See npl in Genome Data Viewer
Location:
chromosome: 4
Exon count:
13
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (100177276..100188847, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (89961816..89973525, complement)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene laminin subunit gamma 1 Neighboring gene DEAH-box helicase 9 Neighboring gene regulator of G-protein signaling 8 Neighboring gene regulator of G-protein signaling 16

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables N-acetylneuraminate lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables N-acetylneuraminate lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables N-acetylneuraminate lyase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in N-acetylneuraminate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within N-acetylneuraminate catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within N-acetylneuraminate catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
N-acetylneuraminate lyase
Names
N-acetylneuraminate pyruvate-lyase
N-acetylneuraminic acid aldolase
NALase
sialate lyase
sialate-pyruvate lyase
sialic acid aldolase
sialic acid lyase
NP_001011207.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011207.1NP_001011207.1  N-acetylneuraminate lyase

    See identical proteins and their annotated locations for NP_001011207.1

    Status: PROVISIONAL

    Source sequence(s)
    BC087756
    UniProtKB/Swiss-Prot
    Q5M905
    UniProtKB/TrEMBL
    A0A6I8RUG4
    Related
    ENSXETP00000033244.4, ENSXETT00000033244.5
    Conserved Domains (1) summary
    cl21457
    Location:8283
    TIM; TIM-like beta/alpha barrel domains

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    100177276..100188847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)