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clpp.L caseinolytic mitochondrial matrix peptidase proteolytic subunit L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 496087, updated on 4-Nov-2024

Summary

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Official Symbol
clpp.L
Official Full Name
caseinolytic mitochondrial matrix peptidase proteolytic subunit L homeolog
Primary source
Xenbase:XB-GENE-969411
Locus tag
XELAEV_18019106mg
See related
EnsemblRapid:ENSXLAG00005002036 AllianceGenome:Xenbase:XB-GENE-969411
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
clpp
Summary
Predicted to enable ATP-dependent peptidase activity; ATPase binding activity; and serine-type endopeptidase activity. Predicted to act upstream of or within protein quality control for misfolded or incompletely synthesized proteins. Predicted to be part of endopeptidase Clp complex. Human ortholog(s) of this gene implicated in Perrault syndrome. Orthologous to human CLPP (caseinolytic mitochondrial matrix peptidase proteolytic subunit). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See clpp.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (150530088..150536441, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (133634170..133640515, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene alkB homolog 7 L homeolog Neighboring gene persephin L homeolog Neighboring gene uncharacterized LOC108711716 Neighboring gene MISP family member 3 L homeolog Neighboring gene paralemmin 3 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC130667

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP-dependent peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase binding IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein quality control for misfolded or incompletely synthesized proteins IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of endopeptidase Clp complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
caseinolytic mitochondrial matrix peptidase proteolytic subunit L homeolog
Names
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095347.1 → NP_001088816.1  caseinolytic mitochondrial matrix peptidase proteolytic subunit L homeolog

    See identical proteins and their annotated locations for NP_001088816.1

    Status: PROVISIONAL

    Source sequence(s)
    BC106236
    UniProtKB/TrEMBL
    A0A974DG57, Q3KQF3, Q5PPT3
    Related
    ENSXLAP00005006124.1, ENSXLAT00005006230.1
    Conserved Domains (1) summary
    PRK00277
    Location:29 → 225
    clpP; ATP-dependent Clp protease proteolytic subunit; Reviewed

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    150530088..150536441 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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