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ubxn2b.L UBX domain protein 2B L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 496062, updated on 4-Nov-2024

Summary

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Official Symbol
ubxn2b.L
Official Full Name
UBX domain protein 2B L homeolog
Primary source
Xenbase:XB-GENE-6252818
Locus tag
XELAEV_18032043mg
See related
EnsemblRapid:ENSXLAG00005015445 AllianceGenome:Xenbase:XB-GENE-6252818
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ubxn2b
Summary
Predicted to enable ubiquitin binding activity. Predicted to act upstream of or within several processes, including autophagosome assembly; nuclear membrane reassembly; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in several cellular components, including Golgi apparatus; centrosome; and endoplasmic reticulum. Orthologous to human UBXN2B (UBX domain protein 2B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ubxn2b.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (124237783..124252073)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (117099283..117113630)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene serine/threonine-protein kinase mig-15-like Neighboring gene family with sequence similarity 110 member B L homeolog Neighboring gene cytochrome P450 family 7 subfamily A member 1 L homeolog Neighboring gene syndecan binding protein L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within Golgi organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within autophagosome assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within membrane fusion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within nuclear membrane reassembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
UBX domain-containing protein 2B
Names
NSFL1 cofactor p37
p97 cofactor p37

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095328.1 → NP_001088797.1  UBX domain-containing protein 2B

    See identical proteins and their annotated locations for NP_001088797.1

    Status: PROVISIONAL

    Source sequence(s)
    BC122501
    UniProtKB/Swiss-Prot
    Q0P3R5, Q5PPW1
    UniProtKB/TrEMBL
    A0A974CNQ3
    Related
    ENSXLAP00005045328.1, ENSXLAT00005046427.1
    Conserved Domains (2) summary
    cd01770
    Location:274 → 350
    p47_UBX; p47-like ubiquitin domain
    smart00553
    Location:159 → 251
    SEP; Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    124237783..124252073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0P3R5.1 GenPept UniProtKB/Swiss-Prot:Q0P3R5

Gene LinkOut

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