rap1gds1.S RAP1, GTP-GDP dissociation stimulator 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rap1gds1.S
Official Full Name: RAP1, GTP-GDP dissociation stimulator 1 S homeolog
Primary source: Xenbase:XB-GENE-6252826
Locus tag: XELAEV_18009443mg
See related: EnsemblRapid:ENSXLAG00005026043 AllianceGenome:Xenbase:XB-GENE-6252826
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: gds1; smggds; XsmgGDS; rap1gds1; rap1gds1-a; rap1gds1-b
Summary: Predicted to enable small GTPase binding activity. Predicted to act upstream of or within positive regulation of GTPase activity and small GTPase-mediated signal transduction. Predicted to be located in cytosol; endoplasmic reticulum; and mitochondrion. Orthologous to human RAP1GDS1 (Rap1 GTPase-GDP dissociation stimulator 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1S

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (63665839..63740623, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (63211356..63287374, complement)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info
enables small GTPase binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of GTPase activity	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within small GTPase-mediated signal transduction	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: rap1 GTPase-GDP dissociation stimulator 1-B

Names: ralB-binding protein B; smgGDS-B; xsmgGDS-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095297.1 → NP_001088766.1 rap1 GTPase-GDP dissociation stimulator 1-B

See identical proteins and their annotated locations for NP_001088766.1

Status: PROVISIONAL

Source sequence(s)

BC087423

UniProtKB/Swiss-Prot

Q5PPZ9

UniProtKB/TrEMBL

A0A974DSD1

Related

ENSXLAP00005077577.1, ENSXLAT00005079168.1

Conserved Domains (2) summary

cd00020
Location:317 → 430

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

sd00043
Location:91 → 116

ARM; armadillo repeat [structural motif]

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

63665839..63740623 complement

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GenBank, FASTA, Sequence Viewer (Graphics)