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fbxo7.S F-box protein 7 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495987, updated on 4-Nov-2024

Summary

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Official Symbol
fbxo7.S
Official Full Name
F-box protein 7 S homeolog
Primary source
Xenbase:XB-GENE-17335514
Locus tag
XELAEV_18019819mg
See related
EnsemblRapid:ENSXLAG00005000596 AllianceGenome:Xenbase:XB-GENE-17335514
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable protein kinase binding activity. Predicted to act upstream of or within positive regulation of autophagy of mitochondrion. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See fbxo7.S in Genome Data Viewer
Location:
chromosome: 3S
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (4429926..4436633, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (4437945..4444774, complement)

Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene LARGE xylosyl- and glucuronyltransferase 1 S homeolog Neighboring gene small nucleolar RNA U3 Neighboring gene synapsin III S homeolog Neighboring gene TIMP metallopeptidase inhibitor 3 S homeolog Neighboring gene E3 ubiquitin/ISG15 ligase TRIM25 Neighboring gene RNA 2',3'-cyclic phosphate and 5'-OH ligase S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables protein kinase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of autophagy of mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC495987

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095254.1 → NP_001088723.1  uncharacterized protein LOC495987

    See identical proteins and their annotated locations for NP_001088723.1

    Status: PREDICTED

    Source sequence(s)
    BC087373
    UniProtKB/TrEMBL
    Q5PQ43
    Related
    ENSXLAP00005001653.1, ENSXLAT00005001693.1
    Conserved Domains (2) summary
    pfam11566
    Location:177 → 277
    PI31_Prot_N; PI31 proteasome regulator N-terminal
    pfam12937
    Location:292 → 338
    F-box-like; F-box-like

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    4429926..4436633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018254391.2 → XP_018109880.1  uncharacterized protein LOC495987 isoform X2

    UniProtKB/TrEMBL
    A0A8J0UMX2
    Related
    ENSXLAP00005001650.1, ENSXLAT00005001690.1

  2. XM_018254390.2 → XP_018109879.1  uncharacterized protein LOC495987 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GQJ3, A0A974D7K5
    Related
    ENSXLAP00005001655.1, ENSXLAT00005001695.1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
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