tgfbi.L transforming growth factor beta induced L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: tgfbi.L
Official Full Name: transforming growth factor beta induced L homeolog
Primary source: Xenbase:XB-GENE-5751318
Locus tag: XELAEV_18017150mg
See related: EnsemblRapid:ENSXLAG00005026001 AllianceGenome:Xenbase:XB-GENE-5751318
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: csd; cdb1; cdg2; csd1; csd2; csd3; ebmd; lcd1; bigh3; cdgg1; tgfbi; xtgfbi; betaig-h3
Summary: Predicted to enable cell adhesion molecule binding activity. Predicted to act upstream of or within cell adhesion and extracellular matrix organization. Predicted to be located in extracellular matrix and extracellular space. Is expressed in anatomical system; pharyngeal arch; and primary germ layer. Human ortholog(s) of this gene implicated in corneal dystrophy (multiple). Orthologous to human TGFBI (transforming growth factor beta induced). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 3L

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3L	NC_054375.1 (43207034..43244574)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3L	NC_030728.1 (28829088..28866626)

Chromosome 3L - NC_054375.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Loss of XTgfbi impaired blastopore formation and dorsal tissue morphogenesis.
Title: The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables cell adhesion molecule binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within extracellular matrix organization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular matrix	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: transforming growth factor beta induced L homeolog

Names: keratoepithelin; transforming growth factor, beta-induced, 68kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.