elavl1.S ELAV like RNA binding protein 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: elavl1.S
Official Full Name: ELAV like RNA binding protein 1 S homeolog
Primary source: Xenbase:XB-GENE-865489
Locus tag: XELAEV_18009899mg
See related: EnsemblRapid:ENSXLAG00005014672 AllianceGenome:Xenbase:XB-GENE-865489
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: hua; hur; ElrA; melg; Xel-1; elav1; elavl1; elavl1-a; elavl1-b
Summary: Enables mRNA 3'-UTR binding activity. Acts upstream of or within intracellular mRNA localization. Located in cell cortex and nucleus. Part of ribonucleoprotein complex. Orthologous to human ELAVL1 (ELAV like RNA binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1S

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1S	NC_054372.1 (95314721..95333038)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1S	NC_030725.1 (90037779..90055865)

Chromosome 1S - NC_054372.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
NOT enables identical protein binding	ISS Inferred from Sequence or Structural Similarity more info
enables mRNA 3'-UTR AU-rich region binding	ISS Inferred from Sequence or Structural Similarity more info
enables mRNA 3'-UTR binding	IDA Inferred from Direct Assay more info	PubMed
enables mRNA 3'-UTR binding	IEA Inferred from Electronic Annotation more info
enables poly(U) RNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within 3'-UTR-mediated mRNA stabilization	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within gastrulation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within gastrulation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within intracellular mRNA localization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mRNA stabilization	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within regulation of stem cell population maintenance	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cell cortex	IDA Inferred from Direct Assay more info	PubMed
located_in cell cortex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: ELAV-like protein 1-B

Names: ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R); Protein ElrA-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095159.1 → NP_001088628.1 ELAV-like protein 1-B

See identical proteins and their annotated locations for NP_001088628.1

Status: PROVISIONAL

Source sequence(s)

BC086269

UniProtKB/Swiss-Prot

Q5U259

Related

ENSXLAP00005042961.1, ENSXLAT00005044029.1

Conserved Domains (4) summary

cd12650
Location:19 → 96

RRM1_Hu; RNA recognition motif 1 in the Hu proteins family

cd12773
Location:106 → 189

RRM2_HuR; RNA recognition motif 2 in vertebrate Hu-antigen R (HuR)

TIGR01661
Location:19 → 326

ELAV_HUD_SF; ELAV/HuD family splicing factor

cl17169
Location:243 → 326

RRM_SF; RNA recognition motif (RRM) superfamily