rab3a.L RAB3A, member RAS oncogene family L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: rab3a.L
Official Full Name: RAB3A, member RAS oncogene family L homeolog
Primary source: Xenbase:XB-GENE-490003
Locus tag: XELAEV_18006377mg
See related: EnsemblRapid:ENSXLAG00005021512 AllianceGenome:Xenbase:XB-GENE-490003
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: rab3a; rab-3a
Summary: Predicted to enable GTP binding activity; GTPase activity; and myosin V binding activity. Predicted to act upstream of or within several processes, including maintenance of presynaptic active zone structure; regulation of vesicle-mediated transport; and secretion by cell. Predicted to be located in several cellular components, including cytoplasmic vesicle; lysosome; and postsynapse. Orthologous to human RAB3A (RAB3A, member RAS oncogene family). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1L

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1L	NC_054371.1 (113381485..113415840)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1L	NC_030724.1 (101326102..101357042)

Chromosome 1L - NC_054371.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables myosin V binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within axonogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within calcium-ion regulated exocytosis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within exocytosis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within maintenance of presynaptic active zone structure	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein localization to plasma membrane	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein secretion	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of exocytosis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of synaptic vesicle fusion to presynaptic active zone membrane	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within synaptic vesicle exocytosis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle docking involved in exocytosis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in lysosome	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in postsynapse	IEA Inferred from Electronic Annotation more info
located_in presynapse	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info
located_in synaptic vesicle	IEA Inferred from Electronic Annotation more info
located_in transport vesicle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RAB3A, member RAS oncogene family L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095062.1 → NP_001088531.1 RAB3A, member RAS oncogene family L homeolog

See identical proteins and their annotated locations for NP_001088531.1

Status: PROVISIONAL

Source sequence(s)

BC084880

UniProtKB/TrEMBL

A0A974DZ49, Q5U507

Related

ENSXLAP00005063201.1, ENSXLAT00005064654.1

Conserved Domains (1) summary

cd01865
Location:22 → 186

Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

113381485..113415840

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041582162.1 → XP_041438096.1 RAB3A, member RAS oncogene family L homeolog isoform X1

UniProtKB/TrEMBL

A0A974DZ49, Q5U507

Conserved Domains (1) summary

cd01865
Location:22 → 186

Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D