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il13ra2.S interleukin 13 receptor subunit alpha 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495398, updated on 4-Nov-2024

Summary

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Official Symbol
il13ra2.S
Official Full Name
interleukin 13 receptor subunit alpha 2 S homeolog
Primary source
Xenbase:XB-GENE-866197
Locus tag
XELAEV_18042296mg
See related
EnsemblRapid:ENSXLAG00005010358 AllianceGenome:Xenbase:XB-GENE-866197
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
il13ra2
Summary
Predicted to enable cytokine receptor activity. Predicted to act upstream of or within cytokine-mediated signaling pathway. Predicted to be located in external side of plasma membrane. Human ortholog(s) of this gene implicated in breast cancer and pancreatic cancer. Orthologous to human IL13RA2 (interleukin 13 receptor subunit alpha 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See il13ra2.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (75229143..75262735, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (72875097..72908700, complement)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 9b S homeolog Neighboring gene 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog Neighboring gene plastin 3 S homeolog Neighboring gene protein FAM162A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
interleukin 13 receptor subunit alpha 2 S homeolog
Names
interleukin 13 receptor, alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001095057.1 → NP_001088526.1  interleukin 13 receptor subunit alpha 2 S homeolog

    See identical proteins and their annotated locations for NP_001088526.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084869
    UniProtKB/TrEMBL
    Q5U516
    Related
    ENSXLAP00005030542.1, ENSXLAT00005031299.1
    Conserved Domains (2) summary
    smart00060
    Location:245 → 303
    FN3; Fibronectin type 3 domain
    pfam09240
    Location:150 → 242
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    75229143..75262735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018232079.1 → XP_018087568.1  interleukin 13 receptor subunit alpha 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8F366, A0A974C400
    Related
    ENSXLAP00005030554.1, ENSXLAT00005031311.1

  2. XM_041574291.1 → XP_041430225.1  interleukin 13 receptor subunit alpha 2 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LNF1
    Related
    ENSXLAP00005030548.1, ENSXLAT00005031305.1
    Conserved Domains (1) summary
    smart00060
    Location:245 → 303
    FN3; Fibronectin type 3 domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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