eml1.S echinoderm microtubule associated protein like 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: eml1.S
Official Full Name: echinoderm microtubule associated protein like 1 S homeolog
Primary source: Xenbase:XB-GENE-949784
Locus tag: XELAEV_18042362mg
See related: EnsemblRapid:ENSXLAG00005009881 AllianceGenome:Xenbase:XB-GENE-949784
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: eml1
Summary: Predicted to enable microtubule binding activity. Predicted to act upstream of or within microtubule cytoskeleton organization. Predicted to be located in mitotic spindle. Human ortholog(s) of this gene implicated in subcortical band heterotopia. Orthologous to human EML1 (EMAP like 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8S

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8S	NC_054386.1 (79159944..79187130)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8S	NC_030739.1 (76770950..76798092)

Chromosome 8S - NC_054386.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables microtubule binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within microtubule cytoskeleton organization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitotic spindle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: echinoderm microtubule associated protein like 1 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001095009.1 → NP_001088478.1 echinoderm microtubule associated protein like 1 S homeolog

See identical proteins and their annotated locations for NP_001088478.1

Status: PROVISIONAL

Source sequence(s)

BC084807

UniProtKB/TrEMBL

A0A974H5X7, Q5U577

Conserved Domains (4) summary

COG2319
Location:219 → 621

WD40; WD40 repeat [General function prediction only]

pfam03451
Location:137 → 210

HELP; HELP motif

sd00039
Location:384 → 419

7WD40; WD40 repeat [structural motif]

cl02567
Location:414 → 776

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...