prpf31.S pre-mRNA processing factor 31 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: prpf31.S
Official Full Name: pre-mRNA processing factor 31 S homeolog
Primary source: Xenbase:XB-GENE-865857
Locus tag: XELAEV_18037696mg
See related: EnsemblRapid:ENSXLAG00005012787 AllianceGenome:Xenbase:XB-GENE-865857
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: rp11; prp31; prpf31
Summary: Predicted to enable U4atac snRNA binding activity. Predicted to act upstream of or within mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 11. Orthologous to human PRPF31 (pre-mRNA processing factor 31). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 7S

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (92206252..92217773)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7S	NC_030737.1 (73058557..73070163)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables U4atac snRNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within spliceosomal tri-snRNP complex assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Cajal body	IEA Inferred from Electronic Annotation more info
part_of MLL1 complex	ISS Inferred from Sequence or Structural Similarity more info
part_of U2-type precatalytic spliceosome	ISS Inferred from Sequence or Structural Similarity more info
part_of U4 snRNP	IEA Inferred from Electronic Annotation more info
part_of U4/U6 x U5 tri-snRNP complex	IEA Inferred from Electronic Annotation more info
part_of U4/U6 x U5 tri-snRNP complex	ISS Inferred from Sequence or Structural Similarity more info
part_of U4atac snRNP	ISS Inferred from Sequence or Structural Similarity more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
part_of precatalytic spliceosome	IEA Inferred from Electronic Annotation more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info
part_of spliceosomal tri-snRNP complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: U4/U6 small nuclear ribonucleoprotein Prp31

Names: PRP31 pre-mRNA processing factor 31 homolog; pre-mRNA-processing factor 31

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094968.1 → NP_001088437.1 U4/U6 small nuclear ribonucleoprotein Prp31

See identical proteins and their annotated locations for NP_001088437.1

Status: PROVISIONAL

Source sequence(s)

BC084759

UniProtKB/Swiss-Prot

Q5U5C5

UniProtKB/TrEMBL

A0A974HAE9

Related

ENSXLAP00005037648.1, ENSXLAT00005038559.1

Conserved Domains (3) summary

smart00931
Location:92 → 143

NOSIC; NOSIC (NUC001) domain

pfam01798
Location:98 → 328

Nop; snoRNA binding domain, fibrillarin

pfam09785
Location:336 → 464

Prp31_C; Prp31 C terminal domain