krt61.L keratin 61 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: krt61.L
Official Full Name: keratin 61 L homeolog
Primary source: Xenbase:XB-GENE-876255
See related: EnsemblRapid:ENSXLAG00005033603 AllianceGenome:Xenbase:XB-GENE-876255
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: krt5; krt5.2; krt61L; krt5.2.L
Summary: Predicted to be a structural constituent of skin epidermis. Predicted to act upstream of or within intermediate filament organization and keratinization. Predicted to be located in cytoplasm; extracellular space; and keratin filament. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2L

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2L	NC_054373.1 (156273189..156277623)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2L	NC_030726.1 (150365230..150369705)

Chromosome 2L - NC_054373.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables structural constituent of skin epidermis	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within intermediate filament organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within keratinization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info
located_in intermediate filament	IEA Inferred from Electronic Annotation more info
located_in keratin filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin 61 L homeolog

Names: keratin 5 L homeolog; keratin 5, gene 2; keratin 5, type II L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094942.1 → NP_001088411.1 keratin 61 L homeolog

See identical proteins and their annotated locations for NP_001088411.1

Status: PROVISIONAL

Source sequence(s)

BC084348

UniProtKB/TrEMBL

Q5XGT4

Related

ENSXLAP00005100278.1, ENSXLAT00005102233.1

Conserved Domains (4) summary

pfam00038
Location:146 → 459

Filament; Intermediate filament protein

pfam16208
Location:18 → 143

Keratin_2_head; Keratin type II head

cl01888
Location:372 → 432

DUF883; Bacterial protein of unknown function (DUF883)

cl23720
Location:208 → 298

RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)