krt17.L keratin 17 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: krt17.L
Official Full Name: keratin 17 L homeolog
Primary source: Xenbase:XB-GENE-865963
Locus tag: XELAEV_18043108mg
See related: EnsemblRapid:ENSXLAG00005036367 AllianceGenome:Xenbase:XB-GENE-865963
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: krt17
Summary: Predicted to enable structural molecule activity. Predicted to act upstream of or within epithelial cell differentiation and intermediate filament organization. Predicted to be located in intermediate filament. Human ortholog(s) of this gene implicated in ectodermal dysplasia; pachyonychia congenita; and steatocystoma multiplex. Orthologous to human KRT17 (keratin 17). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 9_10L

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10L	NC_054387.1 (1091999..1095371)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10L	NC_030740.1 (1052118..1055490)

Chromosome 9_10L - NC_054387.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within epithelial cell differentiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within intermediate filament organization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in intermediate filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin 17 L homeolog

Names: keratin 17, type I L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094941.1 → NP_001088410.1 keratin 17 L homeolog

See identical proteins and their annotated locations for NP_001088410.1

Status: PROVISIONAL

Source sequence(s)

BC084340

UniProtKB/TrEMBL

A0A974BW24, Q5XGU0

Related

ENSXLAP00005108803.1, ENSXLAT00005110967.1

Conserved Domains (2) summary

pfam00038
Location:102 → 413

Filament; Intermediate filament protein

cl12013
Location:267 → 386

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature