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vamp8.L vesicle associated membrane protein 8 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495255, updated on 4-Nov-2024

Summary

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Official Symbol
vamp8.L
Official Full Name
vesicle associated membrane protein 8 L homeolog
Primary source
Xenbase:XB-GENE-6254108
Locus tag
XELAEV_18018603mg
See related
EnsemblRapid:ENSXLAG00005000812 AllianceGenome:Xenbase:XB-GENE-6254108
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
edb; vamp8; cghg07; vamp-8
Summary
Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to act upstream of or within several processes, including SNARE complex assembly; defense response to virus; and mucus secretion. Predicted to be located in cytoplasmic vesicle; lysosomal membrane; and plasma membrane. Predicted to be part of SNARE complex. Orthologous to human VAMP8 (vesicle associated membrane protein 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See vamp8.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (133418461..133429345)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (118047831..118058715)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene gamma-glutamyl carboxylase L homeolog Neighboring gene uncharacterized LOC121401576 Neighboring gene vesicle-associated membrane protein 5-like Neighboring gene transmembrane protein 150A L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An atlas of differential gene expression during early Xenopus embryogenesis. Pollet N, et al. Mech Dev, 2005 Mar. PMID 15763213
  2. Axeldb: a Xenopus laevis database focusing on gene expression. Pollet N, et al. Nucleic Acids Res, 2000 Jan 1. PMID 10592204, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables SNAP receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables syntaxin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within SNARE complex assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within autophagy IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within defense response to virus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mucus secretion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle fusion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SNARE complex IEA
Inferred from Electronic Annotation
more info
  
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mucin granule IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in zymogen granule membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
vesicle associated membrane protein 8 L homeolog
Names
vesicle-associated membrane protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094932.1 → NP_001088401.2  vesicle associated membrane protein 8 L homeolog

    Status: PROVISIONAL

    Source sequence(s)
    BC084290
    UniProtKB/TrEMBL
    A0A1L8H1L5, A0A974HTY3, Q5XGY7
    Related
    ENSXLAP00005002412.1, ENSXLAT00005002458.1
    Conserved Domains (2) summary
    cd15868
    Location:16 → 83
    R-SNARE_VAMP8; SNARE motif of VAMP8
    pfam00957
    Location:17 → 90
    Synaptobrevin; Synaptobrevin

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    133418461..133429345
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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