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gbe1.S glucan (1,4-alpha-), branching enzyme 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495215, updated on 4-Nov-2024

Summary

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Official Symbol
gbe1.S
Official Full Name
glucan (1,4-alpha-), branching enzyme 1 S homeolog
Primary source
Xenbase:XB-GENE-980513
Locus tag
XELAEV_18014241mg
See related
EnsemblRapid:ENSXLAG00005020507 AllianceGenome:Xenbase:XB-GENE-980513
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gbe; gbe1
Summary
Predicted to enable 1,4-alpha-glucan branching enzyme activity; cation binding activity; and hydrolase activity, hydrolyzing O-glycosyl compounds. Predicted to act upstream of or within glycogen biosynthetic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in glycogen storage disease IV and pulmonary tuberculosis. Orthologous to human GBE1 (1,4-alpha-glucan branching enzyme 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gbe1.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (11678965..11732569, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (11619335..11673223, complement)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene roundabout guidance receptor 2 S homeolog Neighboring gene roundabout guidance receptor 1 S homeolog Neighboring gene uncharacterized LOC121400397 Neighboring gene cell adhesion molecule 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 1,4-alpha-glucan branching enzyme activity IEA
Inferred from Electronic Annotation
more info
  
enables cation binding IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glucan (1,4-alpha-), branching enzyme 1 S homeolog
NP_001088368.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094899.1 → NP_001088368.1  glucan (1,4-alpha-), branching enzyme 1 S homeolog

    See identical proteins and their annotated locations for NP_001088368.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084621
    UniProtKB/TrEMBL
    A0A974DHJ2, Q5XG45
    Related
    ENSXLAP00005060066.1, ENSXLAT00005061515.1
    Conserved Domains (4) summary
    cd02854
    Location:68 → 163
    E_set_GBE_euk_N; N-terminal Early set domain associated with the catalytic domain of eukaryotic glycogen branching enzyme (also called 1,4 alpha glucan branching enzyme)
    cd11321
    Location:165 → 570
    AmyAc_bac_euk_BE; Alpha amylase catalytic domain found in bacterial and eukaryotic branching enzymes
    COG0296
    Location:56 → 680
    GlgB; 1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism]
    pfam02806
    Location:588 → 680
    Alpha-amylase_C; Alpha amylase, C-terminal all-beta domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    11678965..11732569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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