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med4.S mediator complex subunit 4 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495214, updated on 4-Nov-2024

Summary

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Official Symbol
med4.S
Official Full Name
mediator complex subunit 4 S homeolog
Primary source
Xenbase:XB-GENE-972357
Locus tag
XELAEV_18015791mg
See related
EnsemblRapid:ENSXLAG00005035499 AllianceGenome:Xenbase:XB-GENE-972357
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
med4
Summary
Predicted to enable transcription coregulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Orthologous to human MED4 (mediator complex subunit 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See med4.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (126422208..126436264, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (117387979..117402819, complement)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled S homeolog Neighboring gene succinate-CoA ligase, ADP-forming, beta subunit S homeolog Neighboring gene retinoblastoma 1 S homeolog Neighboring gene lysophosphatidic acid receptor 6 S homeolog Neighboring gene regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of core mediator complex IEA
Inferred from Electronic Annotation
more info
  
part_of mediator complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mediator of RNA polymerase II transcription subunit 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094898.1 → NP_001088367.1  mediator of RNA polymerase II transcription subunit 4

    See identical proteins and their annotated locations for NP_001088367.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084617
    UniProtKB/Swiss-Prot
    Q5XG48
    UniProtKB/TrEMBL
    A0A974DIP1
    Related
    ENSXLAP00005106159.1, ENSXLAT00005108234.1
    Conserved Domains (1) summary
    pfam10018
    Location:46 → 173
    Med4; Vitamin-D-receptor interacting Mediator subunit 4

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    126422208..126436264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041583206.1 → XP_041439140.1  mediator of RNA polymerase II transcription subunit 4 isoform X1

    UniProtKB/TrEMBL
    A0A8J1MDI0
    Related
    ENSXLAP00005106136.1, ENSXLAT00005108211.1
    Conserved Domains (1) summary
    TIGR03319
    Location:96 → 171
    RNase_Y; ribonuclease Y
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XG48.1 GenPept UniProtKB/Swiss-Prot:Q5XG48

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.