elp4.S elongator acetyltransferase complex subunit 4 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: elp4.S
Official Full Name: elongator acetyltransferase complex subunit 4 S homeolog
Primary source: Xenbase:XB-GENE-991978
Locus tag: XELAEV_18024397mg
See related: EnsemblRapid:ENSXLAG00005005393 AllianceGenome:Xenbase:XB-GENE-991978
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: elp4; paxneb; pax6neb
Summary: Predicted to enable phosphorylase kinase regulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be part of transcription elongation factor complex. Human ortholog(s) of this gene implicated in aniridia. Orthologous to human ELP4 (elongator acetyltransferase complex subunit 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 4S

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4S	NC_054378.1 (9792428..9982884)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4S	NC_030731.1 (9632586..9823630)

Chromosome 4S - NC_054378.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables phosphorylase kinase regulator activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA wobble uridine modification	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
part_of elongator holoenzyme complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription elongation factor complex	IEA Inferred from Electronic Annotation more info
part_of transcription elongation factor complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: elongator complex protein 4

Names: elongation protein 4 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094894.1 → NP_001088363.1 elongator complex protein 4

See identical proteins and their annotated locations for NP_001088363.1

Status: PROVISIONAL

Source sequence(s)

BC084604

UniProtKB/Swiss-Prot

Q5XG58

Related

ENSXLAP00005015919.1, ENSXLAT00005016207.1

Conserved Domains (1) summary

pfam05625
Location:21 → 390

PAXNEB; PAXNEB protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

9792428..9982884

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041591386.1 → XP_041447320.1 elongator complex protein 4 isoform X1

UniProtKB/TrEMBL

A0A8J1N2C4

Related

ENSXLAP00005015923.1, ENSXLAT00005016211.1

Conserved Domains (1) summary

COG0467
Location:47 → 115

RAD55; RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]