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sp8.L Sp8 transcription factor L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495143, updated on 4-Nov-2024

Summary

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Official Symbol
sp8.L
Official Full Name
Sp8 transcription factor L homeolog
Primary source
Xenbase:XB-GENE-1216193
Locus tag
XELAEV_18030945mg
See related
EnsemblRapid:ENSXLAG00005034886 AllianceGenome:Xenbase:XB-GENE-1216193
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
btd; sp8
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and metal ion binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in ectoderm; nervous system; sensory system; and vestibuloauditory system. Orthologous to human SP8 (Sp8 transcription factor). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sp8.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (40027142..40037393, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (36207222..36212887)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette sub-family B member 5-like Neighboring gene ATP-binding cassette sub-family B member 5 Neighboring gene cyclin-O protein B-like Neighboring gene cyclin-O protein B-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transcription factor Sp8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094838.1 → NP_001088307.1  transcription factor Sp8

    See identical proteins and their annotated locations for NP_001088307.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084343
    UniProtKB/Swiss-Prot
    Q5XGT8
    UniProtKB/TrEMBL
    A0A1L8FVZ9, A0A974CLT8
    Related
    ENSXLAP00005104287.1, ENSXLAT00005106310.1
    Conserved Domains (4) summary
    sd00017
    Location:374 → 393
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:429 → 451
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:415 → 438
    zf-H2C2_2; Zinc-finger double domain
    cd22538
    Location:1 → 370
    SP8_N; N-terminal domain of transcription factor Specificity Protein (SP) 8

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    40027142..40037393 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041565540.1 → XP_041421474.1  transcription factor Sp8 isoform X2

    UniProtKB/Swiss-Prot
    Q5XGT8
    UniProtKB/TrEMBL
    A0A1L8FVZ9, A0A974CLT8
    Related
    ENSXLAP00005104317.1, ENSXLAT00005106340.1
    Conserved Domains (4) summary
    sd00017
    Location:374 → 393
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:429 → 451
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:415 → 438
    zf-H2C2_2; Zinc-finger double domain
    cd22538
    Location:1 → 370
    SP8_N; N-terminal domain of transcription factor Specificity Protein (SP) 8

  2. XM_018266634.2 → XP_018122123.1  transcription factor Sp8 isoform X1

    UniProtKB/TrEMBL
    A0A8J0VF23
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XGT8.1 GenPept UniProtKB/Swiss-Prot:Q5XGT8

Gene LinkOut

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