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hibadh.L 3-hydroxyisobutyrate dehydrogenase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 495134, updated on 4-Nov-2024

Summary

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Official Symbol
hibadh.L
Official Full Name
3-hydroxyisobutyrate dehydrogenase L homeolog
Primary source
Xenbase:XB-GENE-17345696
Locus tag
XELAEV_18031001mg
See related
EnsemblRapid:ENSXLAG00005012572 AllianceGenome:Xenbase:XB-GENE-17345696
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable 3-hydroxyisobutyrate dehydrogenase activity; NAD binding activity; and NADP binding activity. Predicted to act upstream of or within valine catabolic process. Predicted to be located in mitochondrion. Orthologous to human HIBADH (3-hydroxyisobutyrate dehydrogenase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hibadh.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (43639965..43713336, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (39842722..39916311, complement)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene homeobox A13 L homeolog Neighboring gene even-skipped homeobox 1 L homeolog Neighboring gene progranulin-like Neighboring gene Tax1 binding protein 1 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 3-hydroxyisobutyrate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within branched-chain amino acid catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within valine catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC495134

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001094829.1 → NP_001088298.1  uncharacterized protein LOC495134

    See identical proteins and their annotated locations for NP_001088298.1

    Status: PREDICTED

    Source sequence(s)
    BC084329
    UniProtKB/TrEMBL
    A0A974HDM9, Q5XGV0
    Related
    ENSXLAP00005036927.1, ENSXLAT00005037831.1
    Conserved Domains (3) summary
    TIGR01692
    Location:37 → 324
    HIBADH; 3-hydroxyisobutyrate dehydrogenase
    pfam03446
    Location:32 → 193
    NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
    pfam14833
    Location:196 → 323
    NAD_binding_11; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    43639965..43713336 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials